NUDT15 抗体 (AA 1-164) (FITC)
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- 抗原 See all NUDT15 抗体
- NUDT15 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15))
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抗原表位
- AA 1-164
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NUDT15 antibody is conjugated to FITC
- 应用范围
- 请咨询
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Nucleotide triphosphate diphosphatase NUDT15 protein (1-164AA)
- 亚型
- IgG
- Top Product
- Discover our top product NUDT15 Primary Antibody
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- NUDT15 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15))
- 别名
- NUDT15 (NUDT15 产品)
- 别名
- MTH2 antibody, RP11-90M2.1 antibody, 6530403O17 antibody, A730068G11Rik antibody, nudix hydrolase 15 antibody, nudix (nucleoside diphosphate linked moiety X)-type motif 15 antibody, NUDT15 antibody, Nudt15 antibody
- 背景
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Background: May catalyze the hydrolysis of nucleoside triphosphates including dGTP, dTTP, dCTP, their oxidized forms like 8-oxo-dGTP and the prodrug thiopurine derivatives 6-thio-dGTP and 6-thio-GTP (PubMed:26238318). Could also catalyze the hydrolysis of some nucleoside diphosphate derivatives (PubMed:22556419, PubMed:26238318). Hydrolyzes oxidized nucleosides triphosphates like 8-oxo-dGTP in vitro, but the specificity and efficiency towards these substrates are low. Therefore, the potential in vivo sanitizing role of this enzyme, that would consist in removing oxidatively damaged forms of nucleosides to prevent their incorporation into DNA, is unclear (PubMed:26238318, PubMed:22556419). Through the hydrolysis of thioguanosine triphosphates may participate in the catabolism of thiopurine drugs (PubMed:26238318, PubMed:25108385). May also have a role in DNA synthesis and cell cycle progression by stabilizing PCNA (PubMed:19419956).
Aliases: 8-dihydro-8-oxoguanine triphosphatase NUDT15 antibody, 8-oxo-dGTPase NUDT15 antibody, A730068G11Rik antibody, EC 3.1.6.- antibody, FLJ10956 antibody, MGC104352 antibody, MTH2 antibody, MutT homolog 2 antibody, Nucleoside diphosphate-linked moiety X motif 15 antibody, NUD15_HUMAN antibody, Nudix (nucleoside diphosphate linked moiety X)-type motif antibody, Nudix motif 15 antibody, NUDT15 antibody, OTTHUMP00000018389 antibody, Probable 7 antibody, Probable 7,8-dihydro-8-oxoguanine triphosphatase NUDT15 antibody, RP11-90M2.1 antibody
- UniProt
- Q9NV35
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