TCEB2 抗体 (AA 1-118)
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- 抗原 See all TCEB2 抗体
- TCEB2 (Transcription Elongation Factor B (SIII), Polypeptide 2 (18kDa, Elongin B) (TCEB2))
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抗原表位
- AA 1-118
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TCEB2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Elongin-B protein (1-118AA)
- 亚型
- IgG
- Top Product
- Discover our top product TCEB2 Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- TCEB2 (Transcription Elongation Factor B (SIII), Polypeptide 2 (18kDa, Elongin B) (TCEB2))
- 别名
- ELOB (TCEB2 产品)
- 别名
- 0610040H15Rik antibody, cb162 antibody, wu:fb47e08 antibody, ELOB antibody, SIII antibody, elongin B antibody, Elob antibody, elob antibody, ELOB antibody
- 背景
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Background: SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). The elongin BC complex seems to be involved as an adapter protein in the proteasomal degradation of target proteins via different E3 ubiquitin ligase complexes, including the von Hippel-Lindau ubiquitination complex CBC(VHL). By binding to BC-box motifs it seems to link target recruitment subunits, like VHL and members of the SOCS box family, to Cullin/RBX1 modules that activate E2 ubiquitination enzymes.
Aliases: EloB antibody, ELOB_HUMAN antibody, Elongin 18 kDa subunit antibody, Elongin B antibody, Elongin-B antibody, RNA polymerase II transcription factor SIII p18 subunit antibody, RNA polymerase II transcription factor SIII subunit B antibody, SIII antibody, SIII p18 antibody, TCEB 2 antibody, Tceb2 antibody, Transcription elongation factor B (SIII) polypeptide 2 antibody, Transcription elongation factor B polypeptide 2 antibody
- UniProt
- Q15370
- 途径
- SARS-CoV-2 Protein Interactome
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