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POLR3C 抗体 (AA 1-534) (FITC)

POLR3C 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7150460
发货至: 中国
  • 抗原 See all POLR3C 抗体
    POLR3C (Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C))
    抗原表位
    • 15
    • 8
    • 8
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-534
    适用
    • 47
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 43
    • 4
    克隆类型
    • 46
    • 1
    多克隆
    标记
    • 20
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This POLR3C antibody is conjugated to FITC
    应用范围
    请咨询
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human DNA-directed RNA polymerase III subunit RPC3 protein (1-534AA)
    亚型
    IgG
    Top Product
    Discover our top product POLR3C Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    POLR3C (Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C))
    别名
    POLR3C (POLR3C 产品)
    别名
    rpc3 antibody, rpc62 antibody, 4933407E01Rik antibody, RPC3 antibody, RPC62 antibody, zgc:56348 antibody, polymerase (RNA) III (DNA directed) polypeptide C (62kD) S homeolog antibody, RNA polymerase III subunit C antibody, polymerase (RNA) III (DNA directed) polypeptide C (62kD) antibody, polymerase (RNA) III (DNA directed) polypeptide C antibody, polr3c.S antibody, POLR3C antibody, polr3c antibody, Polr3c antibody
    背景

    Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the subcomplex RNA Pol III binding to the TFIIIB-DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.

    Aliases: DNA directed III 62 kDa polypeptide antibody, DNA-directed RNA polymerase III subunit C antibody, DNA-directed RNA polymerase III subunit rpc3 antibody, POLR3C antibody, Polymerase (RNA) III (DNA directed) polypeptide C (62kD) antibody, RNA polymerase C subunit 3 antibody, RNA polymerase III 62 kDa subunit antibody, RNA polymerase III C62 subunit antibody, RNA polymerase III subunit C3 antibody, RPC3 antibody, RPC3_HUMAN antibody, RPC62 antibody

    UniProt
    Q9BUI4
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