DACT1 抗体 (AA 410-525) (FITC)
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- 抗原 See all DACT1 抗体
- DACT1 (Dapper, Antagonist of beta-Catenin, Homolog 1 (DACT1))
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抗原表位
- AA 410-525
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DACT1 antibody is conjugated to FITC
- 应用范围
- 请咨询
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Dapper homolog 1 protein (410-525AA)
- 亚型
- IgG
- Top Product
- Discover our top product DACT1 Primary Antibody
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anti-Dapper, Antagonist of beta-Catenin, Homolog 1 (DACT1) (AA 410-525) antibody
DACT1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dapper, Antagonist of beta-Catenin, Homolog 1 (DACT1) (AA 738-836) antibodyDACT1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5D8 unconjugated
anti-Dapper, Antagonist of beta-Catenin, Homolog 1 (DACT1) (AA 725-775) antibodyDACT1 适用: 人, 小鼠, 大鼠, 斑马鱼, 非洲爪蟾, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dapper, Antagonist of beta-Catenin, Homolog 1 (DACT1) (AA 13-41), (N-Term) antibodyDACT1 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB26834 unconjugated
anti-Dapper, Antagonist of beta-Catenin, Homolog 1 (DACT1) (AA 343-392) antibodyDACT1 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, Bat, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Dapper, Antagonist of beta-Catenin, Homolog 1 (DACT1) (AA 139-188) antibodyDACT1 适用: 人, 小鼠, 大鼠, 斑马鱼, 豚鼠, 兔, 犬, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Dapper, Antagonist of beta-Catenin, Homolog 1 (DACT1) (AA 673-722) antibodyDACT1 适用: 人, 小鼠, 豚鼠, 兔, Bat, 猴, 非洲爪蟾, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- DACT1 (Dapper, Antagonist of beta-Catenin, Homolog 1 (DACT1))
- 别名
- DACT1 (DACT1 产品)
- 别名
- XDpr antibody, dpr1 antibody, frodo antibody, hdpr1 antibody, Dapper antibody, thyex3 antibody, dapper1 antibody, MGC89695 antibody, frd1 antibody, frodo1 antibody, 4921528D17Rik antibody, AI115603 antibody, DAPPER antibody, DAPPER1 antibody, FRODO antibody, Frd1 antibody, Frodo1 antibody, MDpr1 antibody, MTNG3 antibody, THYEX3 antibody, DPR1 antibody, HDPR1 antibody, DACT1 antibody, RGD1564008 antibody, XDpr1a antibody, dact1 antibody, dpr antibody, XDpr1b antibody, dishevelled-binding antagonist of beta-catenin 1 antibody, dishevelled binding antagonist of beta catenin 1 antibody, dishevelled-binding antagonist of beta-catenin 1 L homeolog antibody, dishevelled-binding antagonist of beta-catenin 1 S homeolog antibody, dact1 antibody, Dact1 antibody, DACT1 antibody, dact1.L antibody, dact1.S antibody
- 背景
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Background: Involved in regulation of intracellular signaling pathways during development. Specifically thought to play a role in canonical and/or non-canonical Wnt signaling pathways through interaction with DSH (Dishevelled) family proteins. The activation/inhibition of Wnt signaling may depend on the phosphorylation status. Proposed to regulate the degradation of CTNNB1/beta-catenin, thereby modulating the transcriptional activation of target genes of the Wnt signaling pathway. Its function in stabilizing CTNNB1 may involve inhibition of GSK3B activity. Promotes the membrane localization of CTNNB1. The cytoplasmic form can induce DVL2 degradation via a lysosome-dependent mechanism, the function is inhibited by PKA-induced binding to 14-3-3 proteins, such as YWHAB. Seems to be involved in morphogenesis at the primitive streak by regulating VANGL2 and DVL2, the function seems to be independent of canonical Wnt signaling and rather involves the non-canonical Wnt/planar cell polarity (PCP) pathway (By similarity). The nuclear form may prevent the formation of LEF1:CTNNB1 complex and recruit HDAC1 to LEF1 at target gene promoters to repress transcription thus antagonizing Wnt signaling. May be involved in positive regulation of fat cell differentiation. During neuronal differentiation may be involved in excitatory synapse organization, and dendrite formation and establishment of spines.
Aliases: Dact antibody, dact1 antibody, DACT1_HUMAN antibody, Dapper antagonist of beta catenin homolog 1 antibody, Dapper antagonist of catenin 1 antibody, Dapper antibody, Dapper homolog 1 antibody, DAPPER1 antibody, Dpr antibody, Dpr1 antibody, Frd antibody, Frodo antibody, hDPR1 antibody, Hepatocellular carcinoma novel gene 3 protein antibody, Heptacellular carcinoma novel gene 3 antibody, HNG3 antibody, MTNG3 antibody, Thyex3 antibody
- UniProt
- Q9NYF0
- 途径
- Positive Regulation of fat Cell Differentiation
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