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ALOX12B 抗体 (AA 484-663) (FITC)

ALOX12B 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7144526
发货至: 中国
  • 抗原 See all ALOX12B 抗体
    ALOX12B (Arachidonate 12-Lipoxygenase, 12R Type (ALOX12B))
    抗原表位
    • 8
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 484-663
    适用
    • 22
    • 1
    宿主
    • 21
    • 2
    克隆类型
    • 22
    • 1
    多克隆
    标记
    • 11
    • 3
    • 3
    • 2
    • 2
    • 2
    This ALOX12B antibody is conjugated to FITC
    应用范围
    请咨询
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Arachidonate 12-lipoxygenase, 12R-type protein (484-663AA)
    亚型
    IgG
    Top Product
    Discover our top product ALOX12B Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    ALOX12B (Arachidonate 12-Lipoxygenase, 12R Type (ALOX12B))
    别名
    ALOX12B (ALOX12B 产品)
    别名
    ALOX12B antibody, MGC107915 antibody, MGC85124 antibody, 12R-LOX antibody, ARCI2 antibody, Aloxe2 antibody, e-LOX2 antibody, arachidonate 12-lipoxygenase, 12R type antibody, arachidonate 12-lipoxygenase, 12R type S homeolog antibody, ALOX12B antibody, alox12b antibody, alox12b.S antibody, Alox12b antibody
    背景

    Background: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Mainly converts arachidonic acid to (12R)-hydroperoxyeicosatetraenoic acid/(12R)-HPETE and minor stereoisomers. In the skin, acts upstream of ALOXE3 on the lineolate moiety of esterified omega-hydroxyacyl-sphingosine (EOS) ceramides to produce an epoxy-ketone derivative, a crucial step in the conjugation of omega-hydroxyceramide to membrane proteins. Therefore plays a crucial role in the synthesis of corneocytes lipid envelope and the establishment of the skin barrier to water loss. May also play a role in the regulation of the expression of airway mucins.

    Aliases: ALOX12B antibody, Arachidonate 12-lipoxygenase antibody, 12R-type antibody, 12R-LOX antibody, 12R-lipoxygenase antibody, EC 1.13.11.- antibody, Epidermis-type lipoxygenase 12 antibody

    UniProt
    O75342
    途径
    Cell-Cell Junction Organization
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