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- 抗原 See all CAMK4 抗体
- CAMK4 (Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4))
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抗原表位
- pThr196, pThr200
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CAMK4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- 免疫原
- Peptide sequence around phosphorylation site of threonine 200 (M-K-T(p)-V-C) derived from Human CaMK4 or threonine 196 (M-K-T(p)-V-C) derived from Mouse CaMK4.
- 亚型
- IgG
- Top Product
- Discover our top product CAMK4 Primary Antibody
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anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 1-473) antibody
CAMK4 适用: 人 WB, ELISA, IF, IHC (p), RNAi 宿主: 小鼠 Monoclonal 1A3 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 35-292) antibodyCAMK4 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 8C5B8 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) antibodyCAMK4 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 小鼠 Monoclonal 8C5B8 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 304-473) antibodyCAMK4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) antibodyCAMK4 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 35-292) antibodyCAMK4 适用: 人 WB, ELISA, IHC, IF/ICC, FACS 宿主: 小鼠 Monoclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (pThr200) antibodyCAMK4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 1-473) antibodyCAMK4 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 304-473) antibodyCAMK4 适用: 人 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) antibodyCAMK4 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB:1:500-1:1000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CAMK4 (Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4))
- 别名
- CAMK4 (CAMK4 产品)
- 别名
- CaMK IV antibody, CaMK-GR antibody, IV antibody, caMK antibody, CAMK4 antibody, A430110E23Rik antibody, AI666733 antibody, CaMKIV antibody, CaMKIV/Gr antibody, D18Bwg0362e antibody, Ccdpk antibody, RATCCDPK antibody, camk4-A antibody, wu:fj42a03 antibody, zgc:110275 antibody, calcium/calmodulin dependent protein kinase IV antibody, calcium/calmodulin-dependent protein kinase IV antibody, calcium/calmodulin-dependent protein kinase IV L homeolog antibody, CAMK4 antibody, Camk4 antibody, camk4.L antibody, camk4 antibody
- 背景
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Background:
Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK4 signaling cascade and regulates, mainly by phosphorylation, the activity of several transcription activators, such as CREB1, MEF2D, JUN and RORA, which play pivotal roles in immune response, inflammation, and memory consolidation. In the thymus, regulates the CD4+/CD8+ double positive thymocytes selection threshold during T-cell ontogeny. In CD4 memory T-cells, is required to link T-cell antigen receptor (TCR) signaling to the production of IL2, IFNG and IL4 (through the regulation of CREB and MEF2).
Oury F, et al. (2010)Genes Dev 24, 2330-42. Dias WB, Cheung WD, Wang Z, Hart GW (2009) J Biol Chem 284, 21327-37. Chow FA, Anderson KA, Noeldner PK, Means AR (2005)J Biol Chem 280, 20530-8.Aliases: Brain Ca(2+) calmodulin dependent protein kinase type 4 antibody, Brain Ca(2+) calmodulin dependent protein kinase type IV antibody, Brain Ca++-calmodulin dependent protein kinase type IV antibody, Calcium / calmodulin dependent protein kinase type 4 catalytic chain antibody, Calcium / calmodulin dependent protein kinase type IV catalytic chain antibody, Calcium/calmodulin dependent protein kinase IV antibody, Calcium/calmodulin dependent protein kinase type IV antibody, Calcium/calmodulin-dependent protein kinase type IV antibody, CAM kinase 4 antibody, CAM kinase GR antibody, CAM kinase IV antibody, CAM kinase-GR antibody, CaMK 4 antibody, CAMK GR antibody, CaMK IV antibody, Camk4 antibody, CaMKGR antibody, IV antibody, KCC4_HUMAN antibody, MGC36771 antibody
- UniProt
- Q16566
- 途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Production of Molecular Mediator of Immune Response, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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