Recombinant RNF2 抗体
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- 抗原 See all RNF2 抗体
- RNF2 (Ring Finger Protein 2 (RNF2))
- 抗体类型
- Recombinant Antibody
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This RNF2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- Affinity-chromatography
- 免疫原
- A synthesized peptide derived from human RNF20
- 克隆位点
- 2H12
- 亚型
- IgG
- Top Product
- Discover our top product RNF2 Primary Antibody
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anti-Ring Finger Protein 2 (RNF2) (AA 192-290) antibody
RNF2 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 6C2 unconjugated
anti-Ring Finger Protein 2 (RNF2) (AA 192-290) antibodyRNF2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2B6 unconjugated
anti-Ring Finger Protein 2 (RNF2) (AA 1-336) antibodyRNF2 适用: 人 WB, IHC, IF, IP, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 2 (RNF2) (AA 164-223) antibodyRNF2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C1 unconjugated
anti-Ring Finger Protein 2 (RNF2) antibodyRNF2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 2 (RNF2) (Middle Region) antibodyRNF2 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 斑马鱼, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 2 (RNF2) (AA 198-232) antibodyRNF2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB52337 unconjugated
anti-Ring Finger Protein 2 (RNF2) (AA 1-100) antibodyRNF2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 2 (RNF2) (AA 165-199) antibodyRNF2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB52402 unconjugated
anti-Ring Finger Protein 2 (RNF2) (AA 228-277) antibodyRNF2 适用: 人, 小鼠, 大鼠, Cow, 马, 斑马鱼, 兔, Pig, 小鸡, 猴, Hamster, Bat, 非洲爪蟾, 豚鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- RNF2 (Ring Finger Protein 2 (RNF2))
- 别名
- RNF2 (RNF2 产品)
- 别名
- BAP-1 antibody, BAP1 antibody, DING antibody, HIPI3 antibody, RING1B antibody, RING2 antibody, AI326319 antibody, AI450156 antibody, AU019207 antibody, Ring1B antibody, dinG antibody, fa19h05 antibody, ring1b antibody, wu:fa19h05 antibody, wz4556 antibody, bap-1 antibody, bap1 antibody, ding antibody, hipi3 antibody, ring2 antibody, ring finger protein 2 antibody, ring finger protein 2 L homeolog antibody, RNF2 antibody, Rnf2 antibody, rnf2 antibody, rnf2.L antibody
- 背景
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Background: Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role inb histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B, reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes. Recruited to the MDM2 promoter, probably by being recruited by p53/TP53, and thereby acts as a transcriptional coactivator. Mediates the polyubiquitination of isoform 2 of PA2G4 in cancer cells leading to its proteasome-mediated degradation.
Aliases: E3 ubiquitin-protein ligase BRE1A (BRE1-A) (hBRE1) (EC 2.3.2.27) (RING finger protein 20) (RING-type E3 ubiquitin transferase BRE1A), RNF20, BRE1A
- UniProt
- Q5VTR2
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