GNAI1 抗体
-
- 抗原 See all GNAI1 抗体
- GNAI1 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1))
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This GNAI1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95 % as determined by SDS-PAGE
- 免疫原
- guanine nucleotide binding protein(G protein), alpha inhibiting activity polypeptide 1
- 亚型
- IgG
- Top Product
- Discover our top product GNAI1 Primary Antibody
-
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) (AA 1-354) antibody
GNAI1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2B8-2A5 unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) (AA 1-355) antibodyGNAI1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2B8-2A5 unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) (AA 1-354) antibodyGNAI1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) antibodyGNAI1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal R4-5 unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) (Center) antibodyGNAI1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) antibodyGNAI1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) (AA 146-195) antibodyGNAI1 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 兔, 斑马鱼, Drosophila melanogaster, Hamster, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) (AA 1-354) antibodyGNAI1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) (Middle Region) antibodyGNAI1 适用: 人, 小鼠, 大鼠, Cow, Pig, 豚鼠, 犬, 兔, 斑马鱼, 马, 山羊, Saccharomyces cerevisiae, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- 有效期
- 12 months
-
- 抗原
- GNAI1 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1))
- 别名
- GNAI1 (GNAI1 产品)
- 别名
- AU046200 antibody, Gialpha1 antibody, Gnai-1 antibody, gnai1 antibody, Gi antibody, BPGTPB antibody, zgc:63957 antibody, guanine nucleotide binding protein (G protein), alpha inhibiting 1 antibody, G protein subunit alpha i1 antibody, guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 S homeolog antibody, guanine nucleotide-binding protein G(i) subunit alpha-1 antibody, guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 antibody, Gnai1 antibody, gnai1.S antibody, GNAI1 antibody, LOC397505 antibody, gnai1 antibody
- 背景
- Synonyms: Background:Guanine nucleotide-binding proteins(G proteins) function as transducers downstream of G protein-coupled receptors(GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins(PubMed:8774883, PubMed:18434541). Signaling is mediated via effector proteins, such as adenylate cyclase. Inhibits adenylate cyclase activity, leading to decreased intracellular cAMP levels(By similarity). The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. Required for normal cytokinesis during mitosis(PubMed:17635935).
- 分子量
- 40 kDa
- 基因ID
- 2770
- UniProt
- P63096
- 途径
- G-protein mediated Events
-
