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Fibrinogen beta Chain 抗体

This anti-Fibrinogen beta Chain antibody is a 小鼠 单克隆 antibody detecting Fibrinogen beta Chain in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7114194
发货至: 中国

Quick Overview for Fibrinogen beta Chain 抗体 (ABIN7114194)

抗原

See all Fibrinogen beta Chain (FGB) 抗体
Fibrinogen beta Chain (FGB)

适用

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宿主

  • 65
  • 19
  • 1
小鼠

克隆类型

  • 60
  • 25
单克隆

标记

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  • 9
  • 2
  • 2
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  • 2
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  • 2
This Fibrinogen beta Chain antibody is un-conjugated

应用范围

  • 60
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  • 10
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Western Blotting (WB), ELISA

克隆位点

6F4
  • 纯化方法

    Protein A+G purification

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    fibrinogen beta chain

    亚型

    IgG2a
  • 应用备注

    WB: 1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    Fibrinogen beta Chain (FGB)

    别名

    FGB

    背景

    Synonyms:FGB, fibrinogen beta chain Background:Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha(FGA) and fibrinogen gamma(FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.

    分子量

    50 kDa

    基因ID

    2244

    UniProt

    P02675
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