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CYP11A1 抗体 (AA 321-420)

CYP11A1 适用: 人, 大鼠, 小鼠, Cow WB, IF (p), IHC (p), FACS, IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN701530
发货至: 中国
  • 抗原 See all CYP11A1 抗体
    CYP11A1 (Cytochrome P450, Family 11, Subfamily A, Polypeptide 1 (CYP11A1))
    抗原表位
    • 15
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 321-420
    适用
    • 47
    • 24
    • 23
    • 16
    • 2
    • 2
    • 1
    人, 大鼠, 小鼠, Cow
    宿主
    • 49
    • 3
    克隆类型
    • 51
    • 1
    多克隆
    标记
    • 33
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYP11A1 antibody is un-conjugated
    应用范围
    • 49
    • 15
    • 13
    • 12
    • 12
    • 10
    • 8
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    Cow, 人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human CYP11A1/P450SCC
    亚型
    IgG
  • 应用备注
    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Sagaradze, Basalova, Kirpatovsky, Ohobotov, Grigorieva, Balabanyan, Kamalov, Efimenko: "Application of rat cryptorchidism model for the evaluation of mesenchymal stromal cell secretome regenerative potential." in: Biomedicine & pharmacotherapy, Vol. 109, pp. 1428-1436, (2019) (PubMed).

    Ommati, Heidari, Jamshidzadeh, Zamiri, Sun, Sabouri, Wang, Ahmadi, Javanmard, Seifi, Mousapour, Yeganeh: "Dual effects of sulfasalazine on rat sperm characteristics, spermatogenesis, and steroidogenesis in two experimental models." in: Toxicology letters, Vol. 284, pp. 46-55, (2018) (PubMed).

    Medwid, Guan, Yang: "Prenatal exposure to bisphenol A disrupts adrenal steroidogenesis in adult mouse offspring." in: Environmental toxicology and pharmacology, Vol. 43, pp. 203-8, (2016) (PubMed).

    Mahata, Zhang, Kolodziejczyk, Proserpio, Haim-Vilmovsky, Taylor, Hebenstreit, Dingler, Moignard, Göttgens, Arlt, McKenzie, Teichmann: "Single-cell RNA sequencing reveals T helper cells synthesizing steroids de novo to contribute to immune homeostasis." in: Cell reports, Vol. 7, Issue 4, pp. 1130-42, (2014) (PubMed).

    Hu, Dong, Chen, Lu, Han, Qiu, Chen, Qin, Li, Gu, Xia, Sun, Li, Wang: "Low-dose monobutyl phthalate stimulates steroidogenesis through steroidogenic acute regulatory protein regulated by SF-1, GATA-4 and C/EBP-beta in mouse Leydig tumor cells." in: Reproductive biology and endocrinology : RB&E, Vol. 11, pp. 72, (2013) (PubMed).

  • 抗原
    CYP11A1 (Cytochrome P450, Family 11, Subfamily A, Polypeptide 1 (CYP11A1))
    别名
    CYP11A1 (CYP11A1 产品)
    别名
    CYP11A antibody, CYP11A1 antibody, CYPXIA1 antibody, P450SCC antibody, Cyp11a antibody, Cypxia1 antibody, D9Ertd411e antibody, P450scc antibody, Scc antibody, cscc antibody, P450(scc) antibody, SSC antibody, cytochrome P450 family 11 subfamily A member 1 antibody, cholesterol side-chain cleavage enzyme, mitochondrial-like antibody, cytochrome P450 cholesterol side-chain cleavage antibody, cytochrome P450, family 11, subfamily a, polypeptide 1 antibody, cytochrome P450, family 11, subfamily A, polypeptide 1 antibody, CYP11A1 antibody, LOC101827747 antibody, Cyp11a1 antibody
    背景

    Synonyms: CYP11A, CYPXIA1, P45SCC, Cholesterol side-chain cleavage enzyme, mitochondrial, Cholesterol desmolase, Cytochrome P45 11A1, Cytochrome P45(scc), CYP11A1

    Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008]

    基因ID
    1583
    UniProt
    P05108
    途径
    Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin
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