CYP11A1 抗体 (AA 321-420)
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- 抗原 See all CYP11A1 抗体
- CYP11A1 (Cytochrome P450, Family 11, Subfamily A, Polypeptide 1 (CYP11A1))
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抗原表位
- AA 321-420
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适用
- 人, 大鼠, 小鼠, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CYP11A1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- Cow, 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CYP11A1/P450SCC
- 亚型
- IgG
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- 应用备注
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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Application of rat cryptorchidism model for the evaluation of mesenchymal stromal cell secretome regenerative potential." in: Biomedicine & pharmacotherapy, Vol. 109, pp. 1428-1436, (2019) (PubMed).
: "Dual effects of sulfasalazine on rat sperm characteristics, spermatogenesis, and steroidogenesis in two experimental models." in: Toxicology letters, Vol. 284, pp. 46-55, (2018) (PubMed).
: "Prenatal exposure to bisphenol A disrupts adrenal steroidogenesis in adult mouse offspring." in: Environmental toxicology and pharmacology, Vol. 43, pp. 203-8, (2016) (PubMed).
: "Single-cell RNA sequencing reveals T helper cells synthesizing steroids de novo to contribute to immune homeostasis." in: Cell reports, Vol. 7, Issue 4, pp. 1130-42, (2014) (PubMed).
: "Low-dose monobutyl phthalate stimulates steroidogenesis through steroidogenic acute regulatory protein regulated by SF-1, GATA-4 and C/EBP-beta in mouse Leydig tumor cells." in: Reproductive biology and endocrinology : RB&E, Vol. 11, pp. 72, (2013) (PubMed).
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Application of rat cryptorchidism model for the evaluation of mesenchymal stromal cell secretome regenerative potential." in: Biomedicine & pharmacotherapy, Vol. 109, pp. 1428-1436, (2019) (PubMed).
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- 抗原
- CYP11A1 (Cytochrome P450, Family 11, Subfamily A, Polypeptide 1 (CYP11A1))
- 别名
- CYP11A1 (CYP11A1 产品)
- 别名
- CYP11A antibody, CYP11A1 antibody, CYPXIA1 antibody, P450SCC antibody, Cyp11a antibody, Cypxia1 antibody, D9Ertd411e antibody, P450scc antibody, Scc antibody, cscc antibody, P450(scc) antibody, SSC antibody, cytochrome P450 family 11 subfamily A member 1 antibody, cholesterol side-chain cleavage enzyme, mitochondrial-like antibody, cytochrome P450 cholesterol side-chain cleavage antibody, cytochrome P450, family 11, subfamily a, polypeptide 1 antibody, cytochrome P450, family 11, subfamily A, polypeptide 1 antibody, CYP11A1 antibody, LOC101827747 antibody, Cyp11a1 antibody
- 背景
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Synonyms: CYP11A, CYPXIA1, P45SCC, Cholesterol side-chain cleavage enzyme, mitochondrial, Cholesterol desmolase, Cytochrome P45 11A1, Cytochrome P45(scc), CYP11A1
Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008]
- 基因ID
- 1583
- UniProt
- P05108
- 途径
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin
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