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CD46 抗体

CD46 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7257098
发货至: 中国
  • 抗原 See all CD46 抗体
    CD46
    适用
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    宿主
    • 83
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    克隆类型
    • 72
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    多克隆
    标记
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    This CD46 antibody is un-conjugated
    应用范围
    • 90
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    Western Blotting (WB), Immunofluorescence (IF)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human CD46 (NP_722548.1).
    亚型
    IgG
    Top Product
    Discover our top product CD46 Primary Antibody
  • 应用备注
    WB 1:500-1:2000 IF 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CD46
    别名
    CD46 (CD46 产品)
    别名
    AHUS2 antibody, MCP antibody, MIC10 antibody, TLX antibody, TRA2.10 antibody, Mcp antibody, CD46 antibody, CD46 molecule antibody, CD46 antigen, complement regulatory protein antibody, CD46 molecule, complement regulatory protein antibody, membrane cofactor protein-like antibody, CD46 antibody, Cd46 antibody, LOC100341359 antibody, LOC103789310 antibody
    背景
    The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
    分子量

    Observed_MW: 44 kDa

    Calculated_MW: 36 kDa/39 kDa/40 kDa/41 kDa/42 kDa/43 kDa/44 kDa

    基因ID
    4179
    UniProt
    P15529
    途径
    Regulation of Actin Filament Polymerization
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