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ZNHIT3 抗体

ZNHIT3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7248236
发货至: 中国
  • 抗原 See all ZNHIT3 抗体
    ZNHIT3 (Zinc Finger, HIT-Type Containing 3 (ZNHIT3))
    适用
    • 10
    • 2
    • 1
    • 1
    • 1
    宿主
    • 9
    • 1
    克隆类型
    • 9
    • 1
    多克隆
    标记
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZNHIT3 antibody is un-conjugated
    应用范围
    • 3
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen affinity purification
    免疫原
    Synthetic peptide of human ZNHIT3
    亚型
    IgG
    Top Product
    Discover our top product ZNHIT3 Primary Antibody
  • 应用备注
    IHC 1:40-1:250, ELISA 1:5000-1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.9 mg/mL
    缓冲液
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ZNHIT3 (Zinc Finger, HIT-Type Containing 3 (ZNHIT3))
    别名
    ZNHIT3 (ZNHIT3 产品)
    别名
    Myohd1 antibody, Trip3 antibody, TRIP3 antibody, TRIP-3 antibody, zinc finger, HIT type 3 antibody, zinc finger HIT-type containing 3 antibody, zinc finger, HIT-type containing 3 antibody, Znhit3 antibody, ZNHIT3 antibody
    背景
    ZNHIT3 (zinc finger, HIT-type containing 3), also known as TRIP3 (thyroid receptor-interacting protein 3) or HNF-4a coactivator, is a 155 amino acid protein that contains one HIT-type zinc finger and regulates PPAR-mediated adipocyte differentiation. ZNHIT3 also coactivates HNF-4, and as a thyroid receptor interacting protein, ZNHIT3 interacts with the ligand binding domain of the thyroid receptor. The gene encoding ZNHIT3 maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
    UniProt
    Q15649
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