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- 抗原 See all ZZZ3 抗体
- ZZZ3 (Zinc Finger, ZZ-Type Containing 3 (ZZZ3))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ZZZ3 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Antigen affinity purification
- 免疫原
- Fusion protein of human ZZZ3
- 亚型
- IgG
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anti-Zinc Finger, ZZ-Type Containing 3 (ZZZ3) (Internal Region) antibody
ZZZ3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, ZZ-Type Containing 3 (ZZZ3) (Internal Region) antibodyZZZ3 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, ZZ-Type Containing 3 (ZZZ3) (Internal Region) antibodyZZZ3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, ZZ-Type Containing 3 (ZZZ3) (AA 591-640) antibodyZZZ3 适用: 人, 小鼠, 犬, 马, 小鸡, 兔, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, ZZ-Type Containing 3 (ZZZ3) antibodyZZZ3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, ZZ-Type Containing 3 (ZZZ3) (Middle Region) antibodyZZZ3 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 斑马鱼, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, ZZ-Type Containing 3 (ZZZ3) (AA 341-390) antibodyZZZ3 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IHC 1:40-1:250, ELISA 1:5000-1:10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.8 mg/mL
- 缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- ZZZ3 (Zinc Finger, ZZ-Type Containing 3 (ZZZ3))
- 别名
- ZZZ3 (ZZZ3 产品)
- 别名
- 3110065C23Rik antibody, 6430567E01Rik antibody, AA408566 antibody, AI481057 antibody, AW556059 antibody, R75514 antibody, si:ch211-284g18.3 antibody, wu:fj98c02 antibody, ATAC1 antibody, RGD1565468 antibody, zinc finger ZZ-type containing 3 antibody, zinc finger, ZZ-type containing 3 antibody, ZZ-type zinc finger-containing protein 3 antibody, zinc finger, ZZ domain containing 3 antibody, ZZZ3 antibody, zzz3 antibody, LOC100619668 antibody, Zzz3 antibody
- 背景
- ZZZ3 (ZZ-type zinc finger-containing protein 3) is a 903 amino acid protein that contains one HTH myb-type DNA-binding domain and one ZZ-type zinc finger. Phosphorylated upon DNA damage by ATM or ATR, ZZZ3 is a subunit of the ATAC complex, which is composed of GCN5, CRP2BP, ADA3, TADA2L, DR1, CCDC101, YEATS2, WDR5 and MBIP. The ATAC complex has histone acetyltransferase activity on histones H3 and H4. ZZZ3 is expressed as four isoforms produced by alternative splicing and is encoded by a gene mapping to human chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.
- UniProt
- Q8IYH5
- 途径
- Chromatin Binding
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