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WNT5B 抗体 (AA 130-180)

WNT5B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6992093
发货至: 中国
  • 抗原 See all WNT5B 抗体
    WNT5B (Wingless-Type MMTV Integration Site Family, Member 5B (WNT5B))
    抗原表位
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 130-180
    适用
    • 34
    • 20
    • 10
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 32
    • 4
    克隆类型
    • 33
    • 3
    多克隆
    标记
    • 24
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WNT5B antibody is un-conjugated
    应用范围
    • 23
    • 10
    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    WNT5 antibody is human, mouse and rat reactive. WNT5 antibody will detect both WNT5A and WNT5B. At least two isoforms of WNT5B are known to exist, this antibody will detect both isoforms.
    纯化方法
    WNT5 antibody is affinity chromatography purified via peptide column.
    免疫原
    WNT5 antibody was raised against a 15 amino acid peptide near the center of human WNT5B. The immunogen is located within amino acids 130 - 180 of WNT5.
    亚型
    IgG
    Top Product
    Discover our top product WNT5B Primary Antibody
  • 应用备注
    WNT5 antibody can be used for detection of WNT5 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunohistochemistry in rat samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    WNT5 antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    WNT5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原
    WNT5B (Wingless-Type MMTV Integration Site Family, Member 5B (WNT5B))
    别名
    WNT5 (WNT5B 产品)
    别名
    wnt-5b antibody, xwnt5b antibody, WNT5B antibody, AW545702 antibody, Wnt-5b antibody, xwnt-5c antibody, CHUNP6928 antibody, id:ibd5111 antibody, ppt antibody, wnt-5 antibody, wnt5 antibody, wnt[b] antibody, wu:fk85g06 antibody, Wnt family member 5B antibody, wingless-type MMTV integration site family, member 5B antibody, Wnt family member 5B S homeolog antibody, wingless-type MMTV integration site family, member 5b antibody, wnt5b antibody, WNT5B antibody, Wnt5b antibody, wnt5b.S antibody
    背景
    WNT5A and WNT5B are near-identical members of the WNT gene family, which consists of structurally related genes which encode secreted signaling proteins that have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis (1,2). WNT5A and WNT5B coordinate chondrocyte proliferation and differentiation by differentially regulating cyclin D1 and p130 expression, as well as chondrocyte-specific Col2a1 expression (3). Up-regulation of WNT5A and WNT5B has been observed in several types of human cancers, suggesting that they may be useful as diagnostic markers or potent therapeutic targets (4).
    分子量
    Predicted: 39 kDa

    Observed: 465 kDa
    基因ID
    81029
    NCBI登录号
    NP_110402
    UniProt
    Q9H1J7
    途径
    WNT signaling, Embryonic Body Morphogenesis, Positive Regulation of fat Cell Differentiation
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