APBA1 抗体 (N-Term)
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- 抗原 See all APBA1 抗体
- APBA1 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1))
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抗原表位
- AA 90-140, N-Term
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This APBA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- 特异性
- At least two alternatively spliced isoforms are known to exist, this antibody will detect both isoforms. This antibody is predicted to not cross-react with other APBA proteins.
- 纯化方法
- APBA1 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- APBA1 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human APBA1. The immunogen is located within amino acids 90 - 140 of APBA1.
- 亚型
- IgG
- Top Product
- Discover our top product APBA1 Primary Antibody
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anti-Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1) (AA 2-265) antibody
APBA1 适用: 小鼠, 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1) (AA 41-90) antibodyAPBA1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1) (N-Term) antibodyAPBA1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1) (AA 451-550) antibodyAPBA1 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1) (N-Term) antibodyAPBA1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1) (Internal Region) antibodyVerified APBA1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
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APBA1 antibody can be used for detection of APBA1 by Western blot at 0.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- APBA1 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- APBA1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- APBA1 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1))
- 别名
- APBA1 (APBA1 产品)
- 别名
- APBA1 antibody, 6430513E09Rik antibody, Lin-10 antibody, Mint antibody, Mint1 antibody, Urop11 antibody, X11 antibody, X11alpha antibody, D9S411E antibody, LIN10 antibody, MINT1 antibody, X11A antibody, X11ALPHA antibody, amyloid beta precursor protein binding family A member 1 antibody, amyloid beta (A4) precursor protein-binding, family A, member 1b antibody, ketopantoate reductase antibody, 2-dehydropantoate 2-reductase antibody, amyloid beta (A4) precursor protein-binding, family A, member 1 (X11) antibody, amyloid beta (A4) precursor protein-binding, family A, member 1 antibody, amyloid beta (A4) precursor protein binding, family A, member 1 antibody, APBA1 antibody, apba1b antibody, apbA1 antibody, apba1 antibody, Apba1 antibody
- 背景
- APBA1 Antibody: The Amyloid beta 4 (A4) precursor protein-binding family A member 1 (APBA1) is a member of the X11 protein family and a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). APBA1 stabilizes APP and inhibits production of proteolytic APP fragments including the Aβ, peptide that is deposited in the brains of Alzheimer's disease patients. It is thought to be involved in signal transduction processes and is a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. APBA1 can also bind to CASK, a multidomain scaffolding protein involved in brain development and synapse formation.
- 分子量
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Predicted: 92 kDa
Observed: 92 kDa - 基因ID
- 320
- NCBI登录号
- NP_001154
- UniProt
- Q02410
- 途径
- Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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