NLRP7 抗体 (N-Term)
NLRP7
适用: 人
ELISA, WB, IHC (p), IF
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all NLRP7 抗体
- NLRP7 (NLR Family, Pyrin Domain Containing 7 (NLRP7))
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抗原表位
- AA 90-140, N-Term
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NLRP7 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 纯化方法
- NALP7 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- NALP7 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human NALP7. The immunogen is located within amino acids 90 - 140 of NALP7.
- 亚型
- IgG
- Top Product
- Discover our top product NLRP7 Primary Antibody
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anti-NLR Family, Pyrin Domain Containing 7 (NLRP7) (AA 89-187) antibody
NLRP7 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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NALP7 antibody can be used for detection of NALP7 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- NALP7 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- NALP7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- NLRP7 (NLR Family, Pyrin Domain Containing 7 (NLRP7))
- 别名
- NALP7 (NLRP7 产品)
- 别名
- CLR19.4 antibody, HYDM antibody, NALP7 antibody, NOD12 antibody, PAN7 antibody, PYPAF3 antibody, NLR family pyrin domain containing 7 antibody, NLRP7 antibody
- 背景
- NALP7 Antibody: NOD proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins. NALP7, also known as PYPAF3, a member of the related PYRIN-containing APAF1-like proteins (PYPAFs/NALPs) is thought to play a crucial role in cell proliferation. NALP7 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It is expressed in numerous tissues including uterus and ovary, with low levels in heart and brain. NALP7 inhibits caspase-1-dependent interleukin-1β, secretion and is a feedback regulator of interleukin-1β, secretion. Defects in the NALP7 gene are known to cause the formation of a hydatidiform mole (HYDM) and reduce the growth of carcinoma cell lines.
- 基因ID
- 199713
- NCBI登录号
- NP_631915
- UniProt
- Q8WX94
- 途径
- Inflammasome
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