TAB3 抗体 (N-Term)
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- 抗原 See all TAB3 抗体
- TAB3 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))
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抗原表位
- AA 40-90, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TAB3 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- TAB3 antibody is human specific. TAB3 antibody is predicted not to cross-react with other TAB proteins.
- 纯化方法
- TAB3 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- TAB3 antibody was raised against a 13 amino acid synthetic peptide near the amino terminus of human TAB3. The immunogen is located within amino acids 40 - 90 of TAB3.
- 亚型
- IgG
- Top Product
- Discover our top product TAB3 Primary Antibody
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anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) antibody
TAB3 适用: 人, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) (AA 361-712) antibodyTAB3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) antibodyTAB3 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) (Internal Region) antibodyTAB3 适用: 人, 小鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) (AA 50-100) antibodyTAB3 适用: 人, 小鼠, 犬, 小鸡, Cow, Opossum WB 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) (Internal Region) antibodyVerified TAB3 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) (AA 50-100) antibodyTAB3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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TAB3 antibody can be used for detection of TAB3 by immunohistochemistry at 5 μ,g/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- TAB3 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- TAB3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- TAB3 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))
- 别名
- TAB3 (TAB3 产品)
- 别名
- MAP3K7IP3 antibody, NAP1 antibody, 4921526G09Rik antibody, Map3k7ip3 antibody, mKIAA4135 antibody, map3k7ip3 antibody, nap1 antibody, tab3 antibody, tab3-a antibody, tab3-b antibody, map3k7ip3l antibody, si:ch211-232d19.8 antibody, si:dkey-30h22.6 antibody, TGF-beta activated kinase 1 and MAP3K7 binding protein 3 antibody, TGF-beta activated kinase 1/MAP3K7 binding protein 3 antibody, TGF-beta activated kinase 1/MAP3K7 binding protein 3 S homeolog antibody, TAB3 antibody, Tab3 antibody, tab3.S antibody, tab3 antibody
- 背景
- TAB3 Antibody: TAB3 functions in the NF-kappaB signal transduction pathway. It and the similar and functionally redundant protein TAB2, form a ternary complex with the protein kinase TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. Recent experiments have shown that TAB2 and the related protein TAB3 constitutitvely interact with the autophagy mediator Beclin-1, upon induction of autophagy, these proteins dissociate from Beclin-1 and bind TAK1. Overexpression of TAB2 and TAB3 inhibit autophagy, while their depletion triggers it, suggesting that TAB2 and TAB3 act as a control point for autophagy.
- 基因ID
- 257397
- NCBI登录号
- NP_690000
- UniProt
- Q8N5C8
- 途径
- TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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