PLIN1 抗体
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- 抗原 See all PLIN1 抗体
- PLIN1 (Perilipin 1 (PLIN1))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This PLIN1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))
- 交叉反应
- 人, 小鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Full length protein
- 克隆位点
- 6C2
- 亚型
- IgG
- Top Product
- Discover our top product PLIN1 Primary Antibody
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- 应用备注
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WB 1:300-5000
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- PLIN1 (Perilipin 1 (PLIN1))
- 别名
- Perilipin A (PLIN1 产品)
- 别名
- FPLD4 antibody, PERI antibody, PLIN antibody, PERIA antibody, Plin antibody, 6030432J05Rik antibody, Peri antibody, peri antibody, plin antibody, perilipin antibody, LOC692833 antibody, perilipin 1 antibody, perilipin antibody, perilipin 1 L homeolog antibody, PLIN1 antibody, Plin1 antibody, plin1 antibody, LOC692833 antibody, plin1.L antibody
- 背景
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Synonyms: Perilipin-1, Lipid droplet-associated protein, PLIN1
Background: Perilipins, members of the PAT protein family (named after lipid droplet proteins Perilipin, Adipophilin, and TIP47) are found exclusively at the surface of lipid droplets in adipocytes and steroidogenic cells. They have been suggested to function as regulators of lipolysis and triacylglycerol storage within adipose tissue. Four distinct isoforms ranging from perilipin A (57 kDa) to perilipin D (26 kDa) have been identified and they share an identical amino terminal sequences, and contain 26 consensus protein kinase A (PKA) phosphorylation sites. Perilipin C and D have been detected only in steroidogenic cells. Perilipin A is the most abundant form on the lipid droplets of adipocytes. The phosphorylation of perilipin by PKA, which is accompanied by the phosphorylation and translocation of hormone-sensitive lipase from the cytosol to the lipid droplets, promotes lipolysis. There is evidence for the presence of perilipin A in atheroma plaques suggesting that the protein may be involved in the development of therosclerosis by controlling as in adipocytes the hydrolysis of stored lipids.
- 基因ID
- 5346
- UniProt
- O60240
- 途径
- Lipid Metabolism
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