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MME 抗体 (AA 583-740)

MME 适用: 人 IHC, ELISA, StM, Coat 宿主: 小鼠 Monoclonal MME-2580 unconjugated
产品编号 ABIN6940063
发货至: 中国
  • 抗原 See all MME 抗体
    MME (Membrane Metallo-Endopeptidase (MME))
    抗原表位
    • 16
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    AA 583-740
    适用
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    宿主
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    小鼠
    克隆类型
    • 109
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    单克隆
    标记
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    This MME antibody is un-conjugated
    应用范围
    • 132
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    Immunohistochemistry (IHC), ELISA, Staining Methods (StM), Coating (Coat)
    特异性
    Recognizes a 100 kDa glycoprotein, identified as CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant human CD10 protein fragment (aa 583-740) (exact sequence is proprietary)
    克隆位点
    MME-2580
    亚型
    IgG1 kappa
    Top Product
    Discover our top product MME Primary Antibody
  • 应用备注

    Positive Control: Tonsil, small intestine or kidney (IHC).

    Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    MME (Membrane Metallo-Endopeptidase (MME))
    别名
    MME (MME 产品)
    别名
    CALLA antibody, CD10 antibody, NEP antibody, SFE antibody, 6030454K05Rik antibody, C85356 antibody, Nep antibody, neprilysin antibody, membrane metalloendopeptidase antibody, membrane metallo endopeptidase antibody, membrane metallo-endopeptidase antibody, MME antibody, Mme antibody
    物质类
    Chemical
    分子量
    100kDa
    基因ID
    4311
    UniProt
    P08473
    途径
    RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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