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CD46 抗体

CD46 适用: 人, Baboon FACS, IF 宿主: 小鼠 Monoclonal 169-1-E4-3 unconjugated
产品编号 ABIN6940027
发货至: 中国
  • 抗原 See all CD46 抗体
    CD46
    适用
    • 116
    • 39
    • 20
    • 10
    • 9
    • 1
    人, Baboon
    宿主
    • 84
    • 52
    • 2
    小鼠
    克隆类型
    • 73
    • 65
    单克隆
    标记
    • 51
    • 18
    • 16
    • 9
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD46 antibody is un-conjugated
    应用范围
    • 91
    • 79
    • 42
    • 40
    • 32
    • 19
    • 14
    • 14
    • 14
    • 10
    • 6
    • 6
    • 5
    • 2
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    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF)
    特异性
    Recognizes a protein of 52 kDa-58 kDa, identified as CD46 (also known as membrane cofactor protein, MCP). Its epitope is located on the four immunogenic short consensus repeat (SCR) domains at N-terminus of the protein. CD46 exists as many isoforms in a variety of tissues. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. CD46 functions as a C3b/C4b-binding glycoprotein that inhibits complement activation on host cells. It also serves as a measles virus receptor, an adherence factor for group Streptococcus pyogenes, and a cellular pilus receptor for pathogenic Neisseria.
    无交叉反应
    免疫原
    Stimulated human leukocytes
    克隆位点
    169-1-E4-3
    亚型
    IgG2a kappa
    Top Product
    Discover our top product CD46 Primary Antibody
  • 应用备注

    Positive Control: K562, U937, HL60, HeLa and Jurkat cells and human lymphocytes. Lymph node and tonsil.

    Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    CD46
    别名
    CD46 (CD46 产品)
    别名
    AHUS2 antibody, MCP antibody, MIC10 antibody, TLX antibody, TRA2.10 antibody, Mcp antibody, CD46 antibody, CD46 molecule antibody, CD46 antigen, complement regulatory protein antibody, CD46 molecule, complement regulatory protein antibody, membrane cofactor protein-like antibody, CD46 antibody, Cd46 antibody, LOC100341359 antibody, LOC103789310 antibody
    分子量
    52-58kDa
    基因ID
    4179
    UniProt
    P15529
    途径
    Regulation of Actin Filament Polymerization
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