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CD11c 抗体 (AA 637-827)

ITGAX 适用: 人 ELISA, Coat 宿主: 小鼠 Monoclonal ITGAX-2507 unconjugated
产品编号 ABIN6939821
发货至: 中国
  • 抗原 See all CD11c (ITGAX) 抗体
    CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))
    抗原表位
    • 18
    • 9
    • 8
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 637-827
    适用
    • 163
    • 55
    • 13
    • 12
    • 10
    • 9
    • 9
    • 5
    • 1
    宿主
    • 114
    • 52
    • 18
    • 14
    • 5
    小鼠
    克隆类型
    • 154
    • 44
    • 2
    单克隆
    标记
    • 75
    • 16
    • 16
    • 14
    • 12
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD11c antibody is un-conjugated
    应用范围
    • 124
    • 49
    • 48
    • 47
    • 34
    • 30
    • 19
    • 13
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Coating (Coat)
    特异性
    Recognizes a protein of 145 kDa, identified as CD11c. CD11c (ITGAX), a member of the leukointegrin family, shares the same beta subunit with other members of the leukocyte adhesion molecule family, which includes CD11a (LFA-1), CD11b (MAC-1) and CD11d (ITGAD), but has a unique alpha chain. CD11c has been shown to play a role in phagocytosis, cell migration, and cytokine production by monocytes/macrophages as well as induction of T-cell proliferation by Langerhans cells. CD11c is expressed prominently on the plasma membranes of monocytes, tissue macrophages, NK cells, and most dendritic cells (DCs). A lower level of expression is also observed on neutrophils as a result of its high level of expression on most DCs. An antibody to CD11c may aid in identification of lesions with histiocytic origin. It may also been used as a marker for hairy cell leukemia in paraffin-embedded tissues.
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant fragment of human ITGAX protein (around aa 637-827) (exact sequence is proprietary)
    克隆位点
    ITGAX-2507
    亚型
    IgG1 kappa
    Top Product
    Discover our top product ITGAX Primary Antibody
  • 应用备注

    Positive Control: THP-1 cells. Tonsil or Lymph Node.

    Known Application: ELISA (For coating use Ab at 1-5 μg/mL, order Ab without BSA) Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))
    别名
    ITGAX (ITGAX 产品)
    别名
    CD11C antibody, SLEB6 antibody, RGD1561123 antibody, AI449405 antibody, Cd11c antibody, Cr4 antibody, N418 antibody, integrin subunit alpha X antibody, integrin alpha X antibody, ITGAX antibody, Itgax antibody
    分子量
    145kDa
    基因ID
    3687
    UniProt
    P20702
    途径
    Complement System, Activated T Cell Proliferation, Integrin Complex
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