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ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) (AA 1051-1280) 抗体 (HRP)

ABCB1B 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC (fro), IHC (p) 宿主: 兔 Polyclonal HRP
产品编号 ABIN686986
发货至: 中国
  • 抗原 See all ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) 抗体
    ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B)
    抗原表位
    • 15
    • 8
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1051-1280
    适用
    • 31
    • 23
    • 23
    • 4
    • 4
    • 4
    • 4
    人, 小鼠, 大鼠
    宿主
    • 34
    • 13
    克隆类型
    • 34
    • 13
    多克隆
    标记
    • 13
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    HRP
    应用范围
    • 22
    • 19
    • 18
    • 14
    • 14
    • 6
    • 4
    • 3
    • 3
    • 3
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human MDR1
    亚型
    IgG
    Top Product
    Discover our top product ABCB1B Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B)
    别名
    MDR1 (ABCB1B 产品)
    别名
    ABC20 antibody, CD243 antibody, CLCS antibody, GP170 antibody, MDR1 antibody, P-GP antibody, PGY1 antibody, Abcb1 antibody, Mdr1 antibody, Mdr1b antibody, Pgy-1 antibody, Pgy1 antibody, mdr antibody, ATP binding cassette subfamily B member 1 antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 1B antibody, ATP-binding cassette, subfamily B (MDR/TAP), member 1B antibody, ABCB1 antibody, Abcb1b antibody
    背景

    Synonyms: P-Glycoprotein, Multi Drug Resistance Associated Protein, ABCB1, ATP-binding cassette sub-family B MDR/TAP, member 1, ABC20, CD243, CD243 antigen, CLCS, Multidrug resistance protein 1, P glycoprotein 1, p-GP, gp170, P gp, PGY1.

    Background: P Glycoprotein, the product of the MDR1 gene, is expressed in distinct non-malignant cells, typically cells with secretory and excretory functions. It is assumed to function as an ATP-dependent drug efflux pump with broad substrate specificity. The highest expression of P Glycoprotein has been observed in kidney (proximal tubules), liver (bile canaliculi), adrenal gland and intestine, suggesting that the primary role of P Glycoprotein is in the normal secretion of physiological metabolites and ingested chemicals into bile, urine and the lumen of the intestinal tract. Elevated levels of P Glycoprotein have also been reported in multidrug-resistant cell lines and in colon, endometrial, ovarian, and breast tumors, as well as in sarcomas and leukemias / lymphomas.

    基因ID
    5243
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