MAP1LC3A/B 抗体 (AA 21-121)
(1 reference)-
- 抗原 See all MAP1LC3A/B products
- MAP1LC3A/B (MAP1LC3A,B)
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抗原表位
- AA 21-121
- 适用
- 人, 大鼠, 小鼠, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MAP1LC3A/B antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 兔, 大鼠
- 预测反应
- Dog,Cow,Pig,Horse,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human MAP1A/MAP1B LC3 B
- 亚型
- IgG
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anti-MAP1LC3A,B (AA 100-125), (cleaved) antibody
适用: 人, 小鼠 WB, IHC (p), IF 宿主: 兔 Polyclonal RB28610 unconjugated
anti-MAP1LC3A,B (AA 25-121) antibody适用: 人, 大鼠 FACS, IHC (p), ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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: "Quercetin-Rich Guava (Psidium guajava) Juice in Combination with Trehalose Reduces Autophagy, Apoptosis and Pyroptosis Formation in the Kidney and Pancreas of Type II Diabetic Rats." in: Molecules (Basel, Switzerland), Vol. 21, Issue 3, pp. 334, (2016) (PubMed).
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: "Quercetin-Rich Guava (Psidium guajava) Juice in Combination with Trehalose Reduces Autophagy, Apoptosis and Pyroptosis Formation in the Kidney and Pancreas of Type II Diabetic Rats." in: Molecules (Basel, Switzerland), Vol. 21, Issue 3, pp. 334, (2016) (PubMed).
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- 抗原
- MAP1LC3A/B (MAP1LC3A,B)
- 别名
- MAP1A/MAP1B LC3 A/B (MAP1LC3A/B 产品)
- 别名
- ATG8F antibody, LC3B antibody, MAP1A/1BLC3 antibody, MAP1LC3B-a antibody, Map1lc3 antibody, Mpl3 antibody, zbs559 antibody, 1010001C15Rik antibody, Atg8 antibody, LC3b antibody, microtubule associated protein 1 light chain 3 beta antibody, microtubule-associated protein 1 light chain 3 beta antibody, MAP1LC3B antibody, Map1lc3b antibody
- 背景
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Synonyms: MAP LC3 beta, LC3, Autophagy related protein LC3 A, Autophagy related protein LC3 B, Autophagy related ubiquitin like modier LC3 A, Autophagy related ubiquitin like modier LC3 B, MAP1 light chain 3 like protein 1, MAP1 light chain 3 like protein 2, MAP1A/1B light chain 3 A, MAP1A/1B light chain 3 B, MAP1A/1BLC3, MAP1A/MAP1B LC3 A, MAP1A/MAP1B LC3 B, MAP1ALC3, MAP1BLC3, MAP1LC3A, MAP1LC3B, Microtubule associated protein 1 light chain 3 alpha, Microtubule associated protein 1 light chain 3 beta, Microtubule associated proteins 1A/1B light chain 3, Microtubule associated proteins 1A/1B light chain 3A, Microtubule associated proteins 1A/1B light chain 3B.microtubule-associated proteins 1A/1B light chain 3 beta 2
Background: A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. LC3, a ubiquitin-like modifier protein, is the human homolog of yeast Apg8 and is involved in the formation of autophagosomal vacuoles, called autophagosomes. LC3 is expressed as 3 splice variants (LC3A, LC3B and LC3C), which exhibit different tissue distributions and are processed into cytosolic and autophagosomal membrane-bound forms, termed LC3-I and LC3-II, respectively. A disruption to the autophagic process is now associated with the progression of several cancers, neurodegenerative disorders and cardiac pathologies, where LC3 is widely employed as a marker for autophagy.
- 基因ID
- 81631, 84557
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