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Macrophage Mannose Receptor 1 抗体 (PE)

MRC1 适用: 小鼠 FACS, ICFC 宿主: 大鼠 Monoclonal C068C2 PE
产品编号 ABIN6727449
发货至: 中国
  • 抗原 See all Macrophage Mannose Receptor 1 (MRC1) 抗体
    Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))
    适用
    • 61
    • 38
    • 23
    • 16
    • 1
    • 1
    小鼠
    宿主
    • 42
    • 21
    • 12
    大鼠
    克隆类型
    • 41
    • 30
    单克隆
    标记
    • 33
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    This Macrophage Mannose Receptor 1 antibody is conjugated to PE
    应用范围
    • 52
    • 40
    • 23
    • 16
    • 13
    • 11
    • 9
    • 8
    • 6
    • 5
    • 5
    • 4
    • 2
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    • 1
    Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
    克隆位点
    C068C2
    亚型
    IgG2a, kappa
    Top Product
    Discover our top product MRC1 Primary Antibody
  • 应用备注
    Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].
    说明

    Matching Isotype Control: PE Rat IgG2a, κ Isotype Control (ABIN7469840)

    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    PBS with 0.05 % Proclin300, 1 % BSA
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
  • 抗原
    Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))
    别名
    CD206 (MRC1 产品)
    别名
    CD206 antibody, CLEC13D antibody, CLEC13DL antibody, MMR antibody, MRC1L1 antibody, bA541I19.1 antibody, AW259686 antibody, MR antibody, mrc1 antibody, MGC86525 antibody, MRC1 antibody, MRC1L-A antibody, mannose receptor C-type 1 antibody, mannose receptor, C type 1 antibody, mannose receptor C-type 1 L homeolog antibody, mediator of replication checkpoint 1 antibody, MRC1 antibody, Mrc1 antibody, mrc1.L antibody, mrc1 antibody
    背景
    MMR,MR,MRC1,macrophage mannose receptor,mannose receptor,CD206, also known as mannose receptor (MR), is a 175 kD type I membrane protein. It is a pattern recognition receptor (PRR) belonging to the C-type lectin superfamily. MR is expressed on macrophages, dendritic cells, Langerhans cells, and hepatic or lymphatic endothelial cells. MR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine through its C-type lectin-like carbohydrate recognition domains, sulfated carbohydrate antigens through its cysteine-rich domain, and collagens through its fibronectin type II domain. MR mediates endocytosis and phagocytosis as well as activation of macrophages and antigen presentation. It plays an important role in host defense and provides a link between innate and adaptive immunity. Recently, MR on lymphatic endothelial cells was found to be involved in leukocyte trafficking and a contributor to the metastatic behavior of cancer cells. It suggests that MR may be a potential target in controlling inflammation and cancer metastasis by targeting the lymphatic vasculature.
    基因ID
    17533
    UniProt
    Q61830
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