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PD-L1 抗体 (Biotin)

PD-L1 适用: 人 FACS 宿主: 小鼠 Monoclonal 29E-2A3 Biotin
产品编号 ABIN6727427
发货至: 中国
  • 抗原 See all PD-L1 抗体
    PD-L1 (CD274 (PD-L1))
    适用
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    宿主
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    小鼠
    克隆类型
    • 108
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    单克隆
    标记
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    This PD-L1 antibody is conjugated to Biotin
    应用范围
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    Flow Cytometry (FACS)
    克隆位点
    29E-2A3
    亚型
    IgG2b, kappa
    Top Product
    Discover our top product PD-L1 Primary Antibody
  • 应用备注
    For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
    说明

    Matching Isotype Control: Biotin Mouse Rat IgG2b, κ Isotype Control (ABIN7469803)

    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS with 0.05 % Proclin300, 1 % BSA
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2~8°C. Do not freeze.
  • 抗原
    PD-L1 (CD274 (PD-L1))
    别名
    PD-L1 (PD-L1 产品)
    别名
    B7-H antibody, B7H1 antibody, PD-L1 antibody, PDCD1L1 antibody, PDCD1LG1 antibody, PDL1 antibody, A530045L16Rik antibody, B7h1 antibody, Pdcd1l1 antibody, Pdcd1lg1 antibody, Pdl1 antibody, RGD1566211 antibody, CD274 molecule antibody, CD274 antigen antibody, programmed cell death 1 ligand 2 antibody, CD274 antibody, Cd274 antibody, PDCD1LG2 antibody
    背景
    B7-H1, PD-L1,Programmed cell death ligand 1,B7 homolog 1,B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1,CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.
    基因ID
    29126
    UniProt
    Q9NZQ7
    途径
    Cancer Immune Checkpoints
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