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RANKL 抗体 (AA 210-317)

TNFSF11 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN672696
发货至: 中国
  • 抗原 See all RANKL (TNFSF11) 抗体
    RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))
    抗原表位
    • 15
    • 15
    • 15
    • 15
    • 15
    • 15
    • 10
    • 9
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 210-317
    适用
    • 166
    • 129
    • 112
    • 45
    • 2
    • 2
    人, 小鼠, 大鼠, 兔
    宿主
    • 155
    • 31
    • 16
    • 5
    • 1
    克隆类型
    • 170
    • 36
    • 2
    多克隆
    标记
    • 76
    • 18
    • 17
    • 11
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    This RANKL antibody is un-conjugated
    应用范围
    • 169
    • 77
    • 77
    • 63
    • 37
    • 29
    • 29
    • 19
    • 13
    • 11
    • 8
    • 7
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠, 兔, 大鼠
    预测反应
    Dog
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human RANKL
    亚型
    IgG
    Top Product
    Discover our top product TNFSF11 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Zhan, Liu, Wang: "The Role of MicroRNA-143-5p in the Differentiation of Dental Pulp Stem Cells into Odontoblasts by Targeting Runx2 via the OPG/RANKL Signaling Pathway." in: Journal of cellular biochemistry, Vol. 119, Issue 1, pp. 536-546, (2018) (PubMed).

    Dolci, Portela, Onofre de Souza, Medeiros Fossati: "Atorvastatin-induced osteoclast inhibition reduces orthodontic relapse." in: American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics, Vol. 151, Issue 3, pp. 528-538, (2017) (PubMed).

    Yu, Gong, Lin, Wang, Liu, Li: "Denervation effectively aggravates rat experimental periodontitis." in: Journal of periodontal research, Vol. 52, Issue 6, pp. 1011-1020, (2017) (PubMed).

    Chen, Fu, Ma, Wu, Li, Li, Shen, Wang: "Intermittent administration of parathyroid hormone ameliorated alveolar bone loss in experimental periodontitis in streptozotocin-induced diabetic rats." in: Archives of oral biology, Vol. 83, pp. 76-84, (2017) (PubMed).

    Chen, Xue, Shen, Mu, Fu: "Curcumin alleviates glucocorticoid-induced osteoporosis through the regulation of the Wnt signaling pathway." in: International journal of molecular medicine, Vol. 37, Issue 2, pp. 329-38, (2016) (PubMed).

    He, Wang, Wang, Tian, Jiang, Ren, Qiu, Fu: "Effect of glucocorticoids on osteoclast function in a mouse model of bone necrosis." in: Molecular medicine reports, Vol. 14, Issue 2, pp. 1054-60, (2016) (PubMed).

    Zhang, Chen, Wei, Liu, Lei, Bai: "Ginsenosides Rg3 attenuates glucocorticoid-induced osteoporosis through regulating BMP-2/BMPR1A/Runx2 signaling pathway." in: Chemico-biological interactions, Vol. 256, pp. 188-97, (2016) (PubMed).

    Xiao, Hu, Li, Li: "Bone fracture healing is delayed in splenectomic rats." in: Life sciences, Vol. 173, pp. 55-61, (2016) (PubMed).

    Zhang, Liu, Li, Bai: "Mycobacterium tuberculosis 10-kDa co-chaperonin regulates the expression levels of receptor activator of nuclear factor-?B ligand and osteoprotegerin in human osteoblasts." in: Experimental and therapeutic medicine, Vol. 9, Issue 3, pp. 919-924, (2015) (PubMed).

    Ota, Urakawa, Kozawa, Ikuta, Hamada, Tsukushi, Shimoyama, Ishiguro, Nishida: "Expression of colony-stimulating factor 1 is associated with occurrence of osteochondral change in pigmented villonodular synovitis." in: Tumour biology, Vol. 36, Issue 7, pp. 5361-7, (2015) (PubMed).

    Yu, Lv, Zhang, Zhang, Xiao, Li: "Expression of neuropeptides and bone remodeling-related factors during periodontal tissue regeneration in denervated rats." in: Journal of molecular histology, Vol. 46, Issue 2, pp. 195-203, (2015) (PubMed).

    Li, Wu, Ma, Hao, Chen, Fu, Chen, Wang: "Oral administration of 5-hydroxytryptophan aggravated periodontitis-induced alveolar bone loss in rats." in: Archives of oral biology, Vol. 60, Issue 5, pp. 789-98, (2015) (PubMed).

    Sun, Wang, Fu, Wang, Bi: "A Crucial Role of IL-17 in Bone Resorption During Rejection of Fresh Bone Xenotransplantation in Rats." in: Cell biochemistry and biophysics, (2014) (PubMed).

    Yang, Li, Yang, Shen, Zou, Zhu, Zhang, Yang, Li: "Efficacy and safety of echinacoside in a rat osteopenia model." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2013, pp. 926928, (2013) (PubMed).

    Lescarbeau, Seib, Prewitz, Werner, Kaplan: "In vitro model of metastasis to bone marrow mediates prostate cancer castration resistant growth through paracrine and extracellular matrix factors." in: PLoS ONE, Vol. 7, Issue 8, pp. e40372, (2012) (PubMed).

  • 抗原
    RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))
    别名
    RANKL (TNFSF11 产品)
    别名
    CD254 antibody, ODF antibody, OPGL antibody, OPTB2 antibody, RANKL antibody, TRANCE antibody, hRANKL2 antibody, sOdf antibody, TNFSF11 antibody, Ly109l antibody, OPG antibody, Trance antibody, cd254 antibody, odf antibody, opgl antibody, optb2 antibody, rankl antibody, sodf antibody, tnfsf11 antibody, trance antibody, TNF superfamily member 11 antibody, tumor necrosis factor (ligand) superfamily, member 11 antibody, TNF receptor superfamily member 11b antibody, TNF superfamily member 11 L homeolog antibody, TNFSF11 antibody, Tnfsf11 antibody, TNFRSF11B antibody, tnfsf11.L antibody
    背景

    Synonyms: ODF, OPGL, sOdf, CD254, OPTB2, RANKL, TRANCE, hRANKL2, Tumor necrosis factor ligand superfamily member 11, Osteoclast differentiation factor, Osteoprotegerin ligand, Receptor activator of nuclear factor kappa-B ligand, TNF-related activation-induced cytokine, TNFSF11

    Background: Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.

    基因ID
    8600
    UniProt
    O14788
    途径
    NF-kappaB Signaling
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