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Collagen Type I 抗体 (AA 1321-1400)

Name: Collagen Type I 抗体 (AA 1321-1400)
SKU: ABIN670386
Availability: OutOfStock

COL1 适用: 人, 大鼠, 小鼠, 兔, 犬, 鱼 WB, ELISA, IHC (fro), IHC (p), IF (p), IF (cc), FACS 宿主: 兔 Polyclonal unconjugated

SW480 lysates probed with Rabbit Anti-Pro-Collagen I Polyclonal Antibody, Unconjugated at 1:5000 for 90 min at 37˚C.

Formalin-fixed and paraffin-embedded rabbit meniscus tissue labeled with Anti-Collagen I Polyclonal Antibody, Unconjugated (ABIN670386) 1:300 followed by conjugation to the secondary PE antibody and DAB staining

Formalin-fixed and paraffin-embedded dog bladder tissue labeled with Anti-Collagen I Polyclonal Antibody, Unconjugated (ABIN670386) 1:200 followed by conjugation to the secondary antibody and DAB staining

IHC

Formalin-fixed and paraffin-embedded rat colon labeled with Anti-Collagen I Polyclonal Antibody, Unconjugated (ABIN670386) 1:200 followed by conjugation to the secondary antibody and DAB staining

IHC

Mouse muscle lysates probed with Rabbit Anti-Pro-Collegen I Polyclonal Antibody, Unconjugated at 1:5000 for 90 min at 37˚C.

Formalin-fixed and paraffin-embedded rat colon labeled with Anti-Collagen I Polyclonal Antibody, Unconjugated 1:200 followed by conjugation to the secondary antibody and DAB staining

IHC (p)

Formalin-fixed and paraffin-embedded dog bladder tissue labeled with Anti-Collagen I Polyclonal Antibody, Unconjugated 1:200 followed by conjugation to the secondary antibody and DAB staining

IHC (p)

7 images

(16 references)

产品编号 ABIN670386

发货至: 中国

Datasheet as PDF

抗原 See all Collagen Type I (COL1) 抗体

Collagen Type I (COL1) (Collagen, Type I (COL1))
抗原表位
16

15

1

1

1

1

1
AA 1321-1400
适用
95

62

59

20

17

17

14

6

4

3

2

2

2

2

2

2

1
人, 大鼠, 小鼠, 兔, 犬, 鱼
宿主
68

35

14
兔
Compatible Secondaries
克隆类型
82

35
多克隆
标记
58

14

7

6

3

3

3

3

3

3

3

3

3

2

2

1
This Collagen Type I antibody is un-conjugated
应用范围
70

46

37

35

32

28

26

25

20

17

17

9

6

6

5

4

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Flow Cytometry (FACS)

特异性

This antibody is produced using a peptide that is found in the C-terminal propeptide region.

交叉反应

犬, 鱼, 人, 小鼠, 兔, 大鼠

预测反应

Cow,Sheep,Horse

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human Collagen I C-terminal propeptide

亚型

IgG

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anti-Collagen, Type I (COL1) antibody (FITC)
COL1 适用: 人, 大鼠, 小鼠, Cow, 哺乳动物 WB, IHC, IP, FACS 宿主: 兔 Polyclonal FITC

anti-Collagen, Type I (COL1) antibody (Biotin)
COL1 适用: 人, 大鼠, 小鼠, Cow, 哺乳动物 WB, ELISA, IHC, IP, FACS 宿主: 兔 Polyclonal Biotin

anti-Collagen, Type I (COL1) antibody (HRP)
COL1 适用: 人, 大鼠, 小鼠, Cow, 哺乳动物 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal HRP

anti-Collagen, Type I (COL1) antibody
COL1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 3G3 unconjugated

anti-Collagen, Type I (COL1) antibody
COL1 适用: 人, 大鼠, 小鼠 IHC (p), IF 宿主: 小鼠 Monoclonal 4H10 unconjugated

anti-Collagen, Type I (COL1) antibody (Biotin)
COL1 适用: 人 ELISA 宿主: 山羊 Polyclonal Biotin

anti-Collagen, Type I (COL1) antibody
COL1 适用: 人, 小鼠, 哺乳动物, 鱼, Amphibian, Avian WB, IHC (fro), IHC (p), IF 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Yang, Shi, Wu, Li, Zhang, Li, Zhai, Jia, Dang: "Caffeic acid phenethyl ester up-regulates antioxidant levels in hepatic stellate cell line T6 via an Nrf2-mediated mitogen activated protein kinases pathway." in: World journal of gastroenterology, Vol. 23, Issue 7, pp. 1203-1214, (2017) (PubMed).

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Cecen, Kozaci, Yuksel, Ustun, Ergur, Havitcioglu: "Biocompatibility and biomechanical characteristics of loofah based scaffolds combined with hydroxyapatite, cellulose, poly-l-lactic acid with chondrocyte-like cells." in: Materials science & engineering. C, Materials for biological applications, Vol. 69, pp. 437-46, (2016) (PubMed).

Wang, Li, Huang, Wang: "The influence of hypoxia during different pregnancy stages on cardiac collagen accumulation in the adult offspring." in: BioMed research international, Vol. 2014, pp. 419805, (2015) (PubMed).

Zhou, Wang, Song, He, He, He: "Antihypertensive and vascular remodelling effects of the imperatorin derivative OW1 in renovascular hypertension rats." in: Clinical and experimental pharmacology & physiology, Vol. 41, Issue 8, pp. 571-8, (2014) (PubMed).

McNary, Athanasiou, Reddi: "Transforming growth factor β-induced superficial zone protein accumulation in the surface zone of articular cartilage is dependent on the cytoskeleton." in: Tissue engineering. Part A, Vol. 20, Issue 5-6, pp. 921-9, (2014) (PubMed).

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Yang, Yang, Tu, Zheng, Cai, Wang: "Strontium enhances osteogenic differentiation of mesenchymal stem cells and in vivo bone formation by activating Wnt/catenin signaling." in: Stem cells (Dayton, Ohio), Vol. 29, Issue 6, pp. 981-91, (2011) (PubMed).
抗原

Collagen Type I (COL1) (Collagen, Type I (COL1))

别名

Collagen 1 (COL1 产品)

别名

collagen type III alpha 1 chain antibody, COL3A1 antibody

背景

Synonyms: Collagen alpha-1(I) chain, Alpha-1 type I collagen, COL1A1, Pro-collagen 1.
Background: This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. Type I collagen levels have been linked to bone growth and formation. Levels of the C-terminal propeptide are indicative of collagen production in vivo. Elevated levels of C-terminal propeptide have been shown in diseases associated with high levels of bone turnover, including Pagets disease, hyperthyroidism, primary hyperparathyroidism and renal osteodystrophy. Slightly elevated levels of C-terminal propeptide have also been documented in some women in early menopause.

分子量

161kDa

基因ID

1277