Nuclear Pore Complex 抗体
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- 抗原
- Nuclear Pore Complex
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适用
- Saccharomyces cerevisiae
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- 非结合性
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应用范围
- Fluorescence Microscopy (FM)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Anti-Nuclear Pore Complex antibody is directed against Nuclear Pore Complex proteins. The antibody is protein G purified from concentrated clarified cell culture supernate. This antibody is directed against yeast NPC protein. Reactivity is expected from human, mouse and rat.
- 免疫原
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Immunogen: Anti-Nuclear Pore Complex Antibody (Monoclonal) was produced by repeated immunizations with yeast nuclear preparations.
Immunogen Type: Native Protein
- 克隆位点
- 39C7
- 亚型
- IgG
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anti-Nuclear Pore Complex antibody
适用: 人, 大鼠, Cow, Pig ICC, IHC, WB, IF 宿主: 小鼠 Monoclonal 39C7 unconjugated
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- 应用备注
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Application Note: Anti-Nuclear Pore Complex Antibody is suitable for use in IF. Specific conditions for reactivity should be optimized by the end user
IF Microscopy Dilution: 1:50-100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.20.01 % (w/v) Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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- 抗原
- Nuclear Pore Complex
- 背景
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Synonyms: mouse anti-Nuclear Pore Complex Antibody, NPC, NUP62, NUP, NUP133
Background: Nuclear Pore Complex Antibodydetects Nuclear Pore Complex proteins. The nuclear pore complex (NPC) is a very large structure made up of at least 50 different proteins that span the double membrane of the nuclear envelope functioning as a gateway for macromolecular traffic between the cytoplasm and the nucleus. Discrete nuclear pore complex proteins or nucleoporins such as NUP98, NUP180 and p62 have been implicated in autoimmune disease and cancer. Patients with primary biliary cirrhosis (PBC) frequently produce autoantibodies against p62 and NUP180 while NUP98 translocations have been found in patients with acute myelogenous leukemia (AML). Anti-Nuclear Pore Complex Antibody is ideal for investigators involved in Cancer and Immunology Research.
Gene Name: Nuclear stain of multiple gene products including Nup62, Nup133
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