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SLC5A5 抗体 (AA 525-618)

SLC5A5 适用: 人, 大鼠, Pig WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN668751
发货至: 中国
  • 抗原 See all SLC5A5 抗体
    SLC5A5 (Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5))
    抗原表位
    • 45
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 525-618
    适用
    • 69
    • 32
    • 30
    • 2
    • 2
    • 1
    人, 大鼠, Pig
    宿主
    • 50
    • 20
    克隆类型
    • 48
    • 20
    多克隆
    标记
    • 24
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLC5A5 antibody is un-conjugated
    应用范围
    • 60
    • 54
    • 21
    • 18
    • 13
    • 11
    • 8
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, Pig, 大鼠
    预测反应
    Mouse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from mouse NIS
    亚型
    IgG
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Yang, Chen, Guo, Li, Tang, Xu, Sun, Ding, Jiang, Cui, Zheng, Duan: "Molecular Mechanisms of 2, 3', 4, 4', 5-Pentachlorobiphenyl-Induced Thyroid Dysfunction in FRTL-5 Cells." in: PLoS ONE, Vol. 10, Issue 3, pp. e0120133, (2015) (PubMed).

    Guo, Yang, Chen, Li, Tang, Cheng, Xie, Liu, Ding, Cui, Zheng, Duan: "Molecular mechanisms of human thyrocyte dysfunction induced by low concentrations of polychlorinated biphenyl 118 through the Akt/FoxO3a/NIS pathway." in: Journal of applied toxicology : JAT, Vol. 35, Issue 9, pp. 992-8, (2015) (PubMed).

    Yao, Pan, Li, Xu, Lin, Wang, Wang: "Effect of sodium/iodide symporter (NIS)-mediated radioiodine therapy on estrogen receptor-negative breast cancer." in: Oncology reports, Vol. 34, Issue 1, pp. 59-66, (2015) (PubMed).

  • 抗原
    SLC5A5 (Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5))
    别名
    NIS (SLC5A5 产品)
    别名
    Na(+)/I(-) cotransporter antibody, Na(+)/I(-) symporter antibody, Nis antibody, solute carrier family 5 member 5 antibody, Slc5a5 antibody
    背景

    Synonyms: Na+/I- cotransporter, Na+/I- symporter, Na+/I- cotransporter, Na+/I- symporter, Na+/I- cotransporter, Na+/I-symporter, NIS, SC5A5_HUMAN, SLC5A5, sodium iodide symporter, Sodium-iodide symporter, Sodium/iodide cotransporter, Solute carrier family 5 sodium iodide symporter member 5, Solute carrier family 5, Solute carrier family 5 member 5.

    Background: catalyzes Na+/I- symporter activity plays a role in iodide transport and thyroid hormone generation.Human Sodium Iodide Symporter (hNIS) is responsible for iodide concentrating ability within thyroid follicular cells. It is a membrane bound glycoprotein with 13 membrane spanning domains and 14 extramembranous domains. It may represent an autoantigen in thyroid.

    基因ID
    114479
    UniProt
    Q99PN0
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