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SLC22A17 抗体 (AA 475-538)

SLC22A17 适用: 人, 大鼠 ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN668691
发货至: 中国
  • 抗原 See all SLC22A17 抗体
    SLC22A17 (Solute Carrier Family 22 (Organic Cation Transporter), Member 17 (SLC22A17))
    抗原表位
    • 14
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 475-538
    适用
    • 25
    • 19
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 大鼠
    宿主
    • 24
    • 1
    克隆类型
    • 25
    多克隆
    标记
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLC22A17 antibody is un-conjugated
    应用范围
    • 20
    • 12
    • 12
    • 8
    • 3
    • 3
    • 2
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 大鼠
    预测反应
    Mouse,Dog,Cow,Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human SLC22A17
    亚型
    IgG
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Wu, Du, Lok, Lo, Xing: "Lipocalin-2 enhances angiogenesis in rat brain endothelial cells via reactive oxygen species and iron-dependent mechanisms." in: Journal of neurochemistry, (2015) (PubMed).

    Cui, Xu, Shen, Tao, Gao, Lv, Du, Fang, Li: "NGALR is overexpressed and regulated by hypomethylation in esophageal squamous cell carcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 23, pp. 7674-81, (2009) (PubMed).

  • 抗原
    SLC22A17 (Solute Carrier Family 22 (Organic Cation Transporter), Member 17 (SLC22A17))
    别名
    Slc22A17 (SLC22A17 产品)
    别名
    1700094C23Rik antibody, 24p3R antibody, AU041908 antibody, AW555662 antibody, BOIT antibody, Boct antibody, mBOCT antibody, BOCT antibody, NGALR antibody, NGALR2 antibody, NGALR3 antibody, hBOIT antibody, rBOCT antibody, solute carrier family 22 member 17 antibody, solute carrier family 22 (organic cation transporter), member 17 antibody, solute carrier family 22, member 17 antibody, SLC22A17 antibody, Slc22a17 antibody
    背景

    Synonyms: BOCT, BOIT, 24p3R, NGALR, hBOIT, NGALR2, NGALR3, Solute carrier family 22 member 17, 24p3 receptor, Brain-type organic cation transporter, Lipocalin-2 receptor, Neutrophil gelatinase-associated lipocalin receptor, SLC22A17

    Background: Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis (By similarity).

    基因ID
    51310
    UniProt
    Q8WUG5
    途径
    Transition Metal Ion Homeostasis
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