GABRB3 抗体 (Cytoplasmic Loop)
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- 抗原 See all GABRB3 抗体
- GABRB3 (gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))
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抗原表位
- Cytoplasmic Loop
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GABRB3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 交叉反应
- 小鼠, 大鼠
- 交叉反应 (详细)
- Cross reactivity with GABA(A) Receptor beta 3 from other species has not been determined.
- 纯化方法
- Anti-GABA(A) Receptor beta 3 Antibody is directed against rat GABA(A) Receptor beta 3. The antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Reactivity is expected from the following species based on 100% sequence homology: mouse.
- 免疫原
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Immunogen: Anti-GABA(A) Receptor beta 3 Antibody was produced by repeated immunizations with recombinant fusion protein from the cytoplasmic loop of the beta 3 subunit.
Immunogen Type: Recombinant Protein
- 亚型
- IgG
- Top Product
- Discover our top product GABRB3 Primary Antibody
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- 应用备注
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Immunohistochemistry Dilution: User Optimized
Application Note: Anti-GABA(A) Receptor beta 3 (Rabbit) antibody suitable for use in Western Blotting and Immunohistochemistry. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 53 kDa in size corresponding to the beta 3 subunit of GABA A receptor in the appropriate cell lysate or extract.
Western Blot Dilution: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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- 抗原
- GABRB3 (gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))
- 别名
- GABA(A) Receptor beta 3 (GABRB3 产品)
- 别名
- GABRB3 antibody, eca5 antibody, LOC100230475 antibody, ECA5 antibody, A230092K12Rik antibody, AW049585 antibody, Cp1 antibody, Gabrb-3 antibody, beta3 antibody, gamma-aminobutyric acid type A receptor beta3 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, beta 3 antibody, gamma-aminobutyric acid type A receptor beta 3 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 antibody, GABRB3 antibody, gabrb3 antibody, Gabrb3 antibody
- 背景
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Synonyms: Gamma-aminobutyric acid receptor subunit beta-3, GABA(A) receptor subunit beta-3, Gabrb3
Background: Anti-GABA(A) Receptor beta 3 Antibody detects GABA(A) Receptor beta 3. Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse. The GABAA-R is a multimeric subunit complex. To date six αs, four βs and four γs, plus alternative splicing variants of some of these subunits, have been identified. Injection in oocytes or mammalian cell lines of cRNA coding for α- and β-subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a γ-subunit is required for benzodiazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different α-subunits of the receptor. GABA(A) receptor beta 3 antibody is ideal for investigators involved in Neuroscience.
Gene Name: GABRB3
- 基因ID
- 24922
- NCBI登录号
- NP_058761
- UniProt
- P63079
- 途径
- Sensory Perception of Sound
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