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- 抗原 See all DLG3 抗体
- DLG3 (Discs, Large Homolog 3 (DLG3))
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抗原表位
- N-Term
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适用
- 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This DLG3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Anti-SAP102 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with SAP102 from Human, Mouse, and Rat based on 100% homology with the immunizing sequence. No cross-reactivity against PSD95, SAP97 or Chapsyn-110. Cross-reactivity with SAP102 from other sources has not been determined. Organelle Markers, Neurobiology research.
- 免疫原
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Immunogen: SAP102 Antibody was produced in mice by repeated immunizations raised against a fusion protein corresponding to an n-terminal region of rat SAP102.
Immunogen Type: Recombinant Protein
- 克隆位点
- S19-2
- 亚型
- IgG1
- Top Product
- Discover our top product DLG3 Primary Antibody
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anti-Discs, Large Homolog 3 (DLG3) (AA 501-600) antibody
DLG3 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 3 (DLG3) (AA 281-380) antibodyDLG3 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2B6 unconjugated
anti-Discs, Large Homolog 3 (DLG3) (AA 1-817) antibodyDLG3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Discs, Large Homolog 3 (DLG3) (AA 464-817) antibodyDLG3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 3 (DLG3) (AA 749-817) antibodyDLG3 适用: 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 3 (DLG3) (AA 648-697) antibodyDLG3 适用: 人, 大鼠, 小鼠, Cow, 豚鼠, 兔, 犬, 马, 斑马鱼, Pig, 猴, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 3 (DLG3) (AA 201-250) antibodyDLG3 适用: 人, 大鼠, 小鼠, Cow, 豚鼠, 兔, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 3 (DLG3) (AA 108-157) antibodyDLG3 适用: 人, 大鼠, 小鼠, Cow, 豚鼠, 兔, 犬, 斑马鱼, Pig, 猴, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 3 (DLG3) (AA 58-107) antibodyDLG3 适用: 人, 大鼠, 小鼠, Cow, 豚鼠, 兔, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 3 (DLG3) (N-Term) antibodyDLG3 适用: 人, 大鼠, 小鼠, Cow, 豚鼠, 兔, 犬, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Immunohistochemistry Dilution: User Optimized
Application Note: Anti-SAP102 Antibody is suitable for WB, IP, and IHC. Expect a band approximately 105 kDa protein, corresponding to the molecular mass of SAP102 on SDS Page immunoblots. Specific conditions for reactivity should be optimized by the end user.
Immunoprecipitation Dilution: User Optimized
Western Blot Dilution: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
0.09 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- RT,4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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- 抗原
- DLG3 (Discs, Large Homolog 3 (DLG3))
- 别名
- SAP102 (DLG3 产品)
- 别名
- MRX antibody, MRX90 antibody, NEDLG antibody, SAP102 antibody, XLMR antibody, DLG3 antibody, fa66c08 antibody, fa66e02 antibody, fd02c12 antibody, fu95c12 antibody, im:7138640 antibody, si:ch211-276g21.1 antibody, wu:fa66c08 antibody, wu:fa66e02 antibody, wu:fd02c12 antibody, wu:fu95c12 antibody, Dlgh3 antibody, mKIAA1232 antibody, MPP3 antibody, 6430514B01 antibody, CSG18 antibody, Dlg3 antibody, Dusp3 antibody, discs large MAGUK scaffold protein 3 antibody, membrane palmitoylated protein 3 antibody, discs, large homolog 3 (Drosophila) antibody, membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) antibody, DLG3 antibody, MPP3 antibody, dlg3 antibody, Dlg3 antibody, Mpp3 antibody
- 背景
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Synonyms: DLG3, MRX90, NEDLG, XLMR, Disks large homolog 3, PSD-95/SAP90-related protein 1, Synapse-associated protein 102, SAP-102
Background: Synapse-associated protein 102 belongs to the membrane-associated guanylate kinase protein family and is a homolog of the Drosophila dis large tumor suppressor protein. SAP102 has extensive sequence homology to the PSD 95 family of proteins that facilitate ion channel clustering at synaptic terminal. SAP102 consists of three 90 amino acids PDZ domains at its amino terminus, a Src homolgy 3 domain and a guanylate kinase domain. All three PDZ domains of SAP102 participate in binding to the NMDA reception, interacting specifically with the carboxy-terminal domain of the N-methyl-D-aspartate receptor 2B (NR2B). The interaction may facilitate AMPA receptor withdrawal from the postsynaptic membrane by inhibiting the ERK/MAPK pathway. SAP102 also interacts with synaptic ras-GTPase activating protein synGAP through its PDZ domains. In general, the SAP102 protein is more highly expressed in non-proliferating cells than in proliferating cells, indicating a role in the negative regulation of cell growth.
Gene Name: Dlg3
- 基因ID
- 58948
- NCBI登录号
- NP_113827
- UniProt
- Q62936
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