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ABCB11 抗体 (C-Term)

ABCB11 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6657515
发货至: 中国
  • 抗原 See all ABCB11 抗体
    ABCB11 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11))
    抗原表位
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    人, 小鼠, 大鼠
    宿主
    • 29
    • 4
    克隆类型
    • 29
    • 4
    多克隆
    标记
    • 19
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ABCB11 antibody is un-conjugated
    应用范围
    • 19
    • 12
    • 11
    • 8
    • 5
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Anti-ABCB11 antibody is directed against human ABCB11 protein.  The product was affinity purified from monospecific antiserum by immunoaffinity purification.  A BLAST analysis was used to suggest reactivity with this protein from human, mouse, and rat based on homology for the immunogen sequence.  Cross reactivity with ABCB11 from other sources has not been determined.
    免疫原

    Immunogen: ABCB11 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a sequence at the C-terminal of human ABCB11, different from the related mouse and rat sequences by three amino acids.

    Immunogen Type: Peptide

    亚型
    IgG
    Top Product
    Discover our top product ABCB11 Primary Antibody
  • 应用备注

    Immunohistochemistry Dilution: 0.5-1 μg/mL

    Application Note: Anti-ABCB11 Antibody is useful for Immunohistochemistry -P and Western Blotting. Positive control rat liver, mouse liver, and SMMC whole cell lysate used at 40 μg load and 0.5 μg/mL incubation in western blot and rat mouse, and human liver tissue for IHC-P. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~146.4 kDa corresponding to the appropriate cell lysate or extract.

    Western Blot Dilution: 0.1-0.5 μg/mL

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式

    Reconstitution Volume: 200μL

    Reconstitution Buffer: Restore with deionized water (or equivalent)

    缓冲液

    Buffer: 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide

    Stabilizer: 5 mg BSA

    0.05 mg Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    RT,4 °C,-20 °C
    储存方法
    Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
  • 抗原
    ABCB11 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11))
    别名
    ABCB11 (ABCB11 产品)
    别名
    ABCB11 antibody, Bsep antibody, ABC16 antibody, BRIC2 antibody, BSEP antibody, PFIC-2 antibody, PFIC2 antibody, PGY4 antibody, SPGP antibody, Lith1 antibody, BSEP/SPGP antibody, Spgp antibody, ATP binding cassette subfamily B member 11 antibody, bile salt export pump antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 11 antibody, ABCB11 antibody, LOC100489744 antibody, LOC100565276 antibody, EDI_111220 antibody, EDI_272930 antibody, abcb11 antibody, Abcb11 antibody
    背景

    Synonyms: ATP-binding cassette sub-family B member 11, BSEP, Bile Salt Export Pump

    Background: Bile Salt Export Pump (BSEP) is a protein which in humans is encoded by the ABCB 11 gene. It is a member of the superfamily of ATP-binding cassette (ABC) transporters, also known as ABCB11. It is mapped to chromosome 2q24. The BSEP protein is mainly expressed in the liver. ABCB11 is a gene associated with progressive familial intrahepatic cholestasis type 2 (PFIC2) which caused by mutations in the ABCB11 gene will increases the risk of hepatocellular carcinoma in early life. This antibody is suitable for researchers interested in signal transduction and cancer research.

    Gene Name: ABCB11

    基因ID
    8647
    NCBI登录号
    NP_003733
    UniProt
    O95342
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