RUNX1T1 抗体 (Internal Region, N-Term)
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- 抗原 See all RUNX1T1 抗体
- RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))
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抗原表位
- Internal Region, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RUNX1T1 antibody is un-conjugated
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应用范围
- ELISA, Chromatin Immunoprecipitation (ChIP)
- 纯化方法
- Anti-ETO Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. This product reacts with human ETO. Cross reactivity with ETO from other sources is not known.
- 免疫原
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Immunogen: Anti-ETO Antibody was produced in rabbits by repeated immunizations with human ETO using two synthetic peptides containing sequences from the N-terminal and internal region of the protein respectively.
Immunogen Type: Peptide
- Top Product
- Discover our top product RUNX1T1 Primary Antibody
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- 应用备注
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Application Note: Anti-ETO Antibody is suitable for Chromatin Immunoprecipitation and ELISA. Specific conditions for reactivity should be optimized by the end user.
ChIP Dilution: 4 μL/ChIP
ELISA Dilution: 1:100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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0.01 % (w/v) Sodium Azide
Stabilizer: None
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- RT,4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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- 抗原
- RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))
- 别名
- ETO (RUNX1T1 产品)
- 别名
- MTG8 antibody, si:ch211-232j17.1 antibody, wu:fi14b07 antibody, zgc:154044 antibody, AML1T1 antibody, CBFA2T1 antibody, CDR antibody, ETO antibody, ZMYND2 antibody, Cbfa2t1h antibody, Cbfa2t1 antibody, runt-related transcription factor 1; translocated to, 1 (cyclin D-related) antibody, RUNX1 translocation partner 1 L homeolog antibody, RUNX1 translocation partner 1 antibody, runx1t1 antibody, runx1t1.L antibody, RUNX1T1 antibody, Runx1t1 antibody
- 背景
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Synonyms: Protein CBFA2T1, Cyclin-D-related protein, Eight twenty one protein, Protein ETO, Protein MTG8, Zinc finger MYND domain-containing protein 2, AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMTND2
Background: ETO is a transcriptional regulator which belongs to the myeloid translocation gene family. ETO exerts its function by interaction with transcription factors bound to promoters and binding to histone deacetylases. It recruits a range of corepressors to facilitate transcriptional repression. The t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukaemia. This translocation produces a chimeric gene made up of the 5'-region of AML1 and the 3'-region of the ETO gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Anti-ETO Antibody is ideal for research in Gene Expression, Transcription and Cancer.
Gene Name: RUNX1T1
- 基因ID
- 862
- NCBI登录号
- NP_001185554
- UniProt
- Q06455
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