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PDE6B 抗体

PDE6B 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6570798
发货至: 中国
  • 抗原 See all PDE6B 抗体
    PDE6B (phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B))
    适用
    • 15
    • 11
    • 9
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 15
    • 1
    克隆类型
    • 16
    多克隆
    标记
    • 14
    • 1
    • 1
    This PDE6B antibody is un-conjugated
    应用范围
    • 13
    • 6
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human PDE6B (NP_001138763.1).
    亚型
    IgG
    Top Product
    Discover our top product PDE6B Primary Antibody
  • 应用备注
    IHC 1:50-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PDE6B (phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B))
    别名
    PDE6B (PDE6B 产品)
    别名
    CSNB3 antibody, CSNBAD2 antibody, PDEB antibody, RP40 antibody, rd1 antibody, PDBS antibody, RCD-1 antibody, Pdeb antibody, r antibody, rd antibody, rd-1 antibody, rd10 antibody, phosphodiesterase 6B antibody, phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide antibody, PDE6B antibody, Pde6b antibody
    背景
    Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
    分子量

    Observed_MW: 98kDa

    Calculated_MW: 66kDa/98kDa

    基因ID
    5158
    UniProt
    P35913
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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