MUS81 抗体
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- 抗原 See all MUS81 抗体
- MUS81 (MUS81 Endonuclease Homolog (MUS81))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MUS81 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human MUS81 (NP_079404.3).
- 亚型
- IgG
- Top Product
- Discover our top product MUS81 Primary Antibody
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- 应用备注
- IHC 1:50-1:100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- MUS81 (MUS81 Endonuclease Homolog (MUS81))
- 别名
- MUS81 (MUS81 产品)
- 别名
- CG3026 antibody, Dmel\\CG3026 antibody, EG:BACR7A4.16 antibody, MUS81 antibody, GB15332 antibody, ARABIDOPSIS THALIANA MMS AND UV SENSITIVE 81 antibody, ATMUS81 antibody, F6I18.220 antibody, F6I18_220 antibody, MMS AND UV SENSITIVE 81 antibody, SLX3 antibody, slx3 antibody, 1200008A18Rik antibody, AI182501 antibody, AW045863 antibody, wu:fc26g01 antibody, zgc:66489 antibody, zgc:91801 antibody, CG3026 gene product from transcript CG3026-RA antibody, MUS81 structure-specific endonuclease subunit antibody, crossover junction endonuclease MUS81 antibody, Restriction endonuclease, type II-like superfamily protein antibody, Mus81p antibody, Holliday junction resolvase subunit Mus81 antibody, MUS81 protein antibody, hypothetical protein antibody, mus81 antibody, MUS81 antibody, LOC725951 antibody, Mus81 antibody, CAALFM_C600540WA antibody
- 背景
- This gene encodes a structure-specific endonuclease which belongs to the XPF/MUS81 endonuclease family and plays a critical role in the resolution of recombination intermediates during DNA repair after inter-strand cross-links, replication fork collapse, and DNA double-strand breaks. The encoded protein associates with one of two closely related essential meiotic endonuclease proteins (EME1 or EME2) to form a complex that processes DNA secondary structures. It contains an N-terminal DEAH helicase domain, an excision repair cross complementation group 4 (ERCC4) endonuclease domain, and two tandem C-terminal helix-hairpin-helix domains. Mice with a homozygous knockout of the orthologous gene have significant meiotic defects including the failure to repair a subset of DNA double strand breaks.
- 分子量
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Observed_MW: 60kDa
Calculated_MW: 61kDa
- 基因ID
- 80198
- UniProt
- Q96NY9
- 途径
- DNA Damage Repair
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