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SUB1 抗体

SUB1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6570210
发货至: 中国
  • 抗原 See all SUB1 抗体
    SUB1 (Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1))
    适用
    • 35
    • 13
    • 9
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 33
    • 2
    克隆类型
    • 34
    • 1
    多克隆
    标记
    • 24
    • 3
    • 3
    • 3
    • 1
    • 1
    This SUB1 antibody is un-conjugated
    应用范围
    • 29
    • 18
    • 15
    • 8
    • 6
    • 4
    • 2
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide of human PABPC4 (NP_003810.1).
    亚型
    IgG
    Top Product
    Discover our top product SUB1 Primary Antibody
  • 应用备注
    IHC 1:50-1:200 IF 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    SUB1 (Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1))
    别名
    PC4 (SUB1 产品)
    别名
    P15 antibody, PC4 antibody, p14 antibody, AI842364 antibody, P9 antibody, Pc4 antibody, Rpo2tc1 antibody, SUB1 homolog, transcriptional regulator antibody, SUB1 homolog (S. cerevisiae) antibody, SUB1 antibody, Sub1 antibody
    背景
    Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    分子量

    Observed_MW: 79kDa

    Calculated_MW: 69kDa/70kDa/72kDa

    基因ID
    8761
    UniProt
    Q13310
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