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TRAF3 抗体

TRAF3 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6569446
发货至: 中国
  • 抗原 See all TRAF3 抗体
    TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))
    适用
    • 59
    • 40
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    • 3
    • 1
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    人, 小鼠, 大鼠
    宿主
    • 56
    • 3
    克隆类型
    • 58
    • 1
    多克隆
    标记
    • 30
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    • 1
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    This TRAF3 antibody is un-conjugated
    应用范围
    • 54
    • 28
    • 14
    • 13
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    • 7
    • 5
    • 4
    • 3
    • 2
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    Immunofluorescence (IF)
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide of human TRAF3
    亚型
    IgG
    Top Product
    Discover our top product TRAF3 Primary Antibody
  • 应用备注
    IF 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))
    别名
    TRAF3 (TRAF3 产品)
    别名
    CAP-1 antibody, CAP1 antibody, CD40bp antibody, CRAF1 antibody, IIAE5 antibody, LAP1 antibody, AI528849 antibody, T-BAM antibody, amn antibody, TNF receptor associated factor 3 antibody, TNF receptor-associated factor 3 antibody, Tnf receptor-associated factor 3 antibody, TRAF3 antibody, Traf3 antibody
    背景
    The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported.
    分子量

    Observed_MW: 70kDa

    Calculated_MW: 55kDa/64kDa

    基因ID
    7187
    UniProt
    Q13114
    途径
    NF-kappaB Signaling, Apoptosis, TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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