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CD59 抗体

CD59 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6568850
发货至: 中国
  • 抗原 See all CD59 抗体
    CD59
    适用
    • 138
    • 14
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    人, 小鼠, 大鼠
    宿主
    • 90
    • 69
    • 6
    • 4
    克隆类型
    • 97
    • 69
    • 1
    多克隆
    标记
    • 78
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    This CD59 antibody is un-conjugated
    应用范围
    • 101
    • 70
    • 46
    • 40
    • 31
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    • 25
    • 15
    • 15
    • 14
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    Immunohistochemistry (IHC)
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human CD59
    亚型
    IgG
    Top Product
    Discover our top product CD59 Primary Antibody
  • 应用备注
    IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CD59
    别名
    CD59 (CD59 产品)
    别名
    16.3A5 antibody, 1F5 antibody, EJ16 antibody, EJ30 antibody, EL32 antibody, G344 antibody, HRF-20 antibody, HRF20 antibody, MAC-IP antibody, MACIF antibody, MEM43 antibody, MIC11 antibody, MIN1 antibody, MIN2 antibody, MIN3 antibody, MIRL antibody, MSK21 antibody, p18-20 antibody, Cd59a antibody, Cd59b antibody, MACIP antibody, CD59 molecule (CD59 blood group) antibody, CD59 molecule antibody, CD59 antibody, Cd59 antibody
    背景
    This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.
    分子量

    Observed_MW: 17kDa

    Calculated_MW: 14kDa

    基因ID
    966
    UniProt
    P13987
    途径
    Complement System
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