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HSD11B1 抗体

HSD11B1 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6568805
发货至: 中国
  • 抗原 See all HSD11B1 抗体
    HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))
    适用
    • 52
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    小鼠
    宿主
    • 49
    • 6
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    克隆类型
    • 46
    • 11
    多克隆
    标记
    • 36
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    This HSD11B1 antibody is un-conjugated
    应用范围
    • 33
    • 18
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    Western Blotting (WB)
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human HSD11B1 (NP_005516.1).
    亚型
    IgG
    Top Product
    Discover our top product HSD11B1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))
    别名
    HSD11B1 (HSD11B1 产品)
    别名
    11-DH antibody, 11-beta-HSD1 antibody, CORTRD2 antibody, HDL antibody, HSD11 antibody, HSD11B antibody, HSD11L antibody, SDR26C1 antibody, hsd11 antibody, hsd11b antibody, LRRGT00065 antibody, hydroxysteroid 11-beta dehydrogenase 1 antibody, hydroxysteroid (11-beta) dehydrogenase 1b antibody, hydroxysteroid (11-beta) dehydrogenase 1 L homeolog antibody, HSD11B1 antibody, HSD11B1b antibody, hsd11b1.L antibody, Hsd11b1 antibody
    背景
    The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.
    分子量

    Observed_MW: 32kDa

    Calculated_MW: 32kDa

    基因ID
    3290
    UniProt
    P28845
    途径
    Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Carbohydrate Metabolic Process
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