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SMG7 抗体

SMG7 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6568670
发货至: 中国
  • 抗原 See all SMG7 抗体
    SMG7 (Smg-7 Homolog, Nonsense Mediated mRNA Decay Factor (SMG7))
    适用
    • 23
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 23
    克隆类型
    • 23
    多克隆
    标记
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SMG7 antibody is un-conjugated
    应用范围
    • 13
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human SMG7 (NP_963863.2).
    亚型
    IgG
    Top Product
    Discover our top product SMG7 Primary Antibody
  • 应用备注
    WB 1:200-1:2000
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    SMG7 (Smg-7 Homolog, Nonsense Mediated mRNA Decay Factor (SMG7))
    别名
    SMG7 (SMG7 产品)
    别名
    9430023P16Rik antibody, mKIAA0250 antibody, C1orf16 antibody, EST1C antibody, SGA56M antibody, Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) antibody, SMG7, nonsense mediated mRNA decay factor antibody, Smg7 antibody, SMG7 antibody
    背景
    SMG7,C1orf16,EST1C,SGA56M,This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD), a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
    分子量

    Observed_MW: 127kDa

    Calculated_MW: 122kDa/127kDa/131kDa

    基因ID
    9887
    UniProt
    Q92540
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