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UGT1A1 抗体

UGT1A1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6568068
发货至: 中国
  • 抗原 See all UGT1A1 抗体
    UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))
    适用
    • 47
    • 15
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 44
    • 2
    • 1
    克隆类型
    • 45
    • 2
    多克隆
    标记
    • 21
    • 5
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UGT1A1 antibody is un-conjugated
    应用范围
    • 29
    • 22
    • 21
    • 18
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB)
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human UGT1A1
    亚型
    IgG
    Top Product
    Discover our top product UGT1A1 Primary Antibody
  • 应用备注
    WB 1:500 - 1:2000
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))
    别名
    UGT1A1 (UGT1A1 产品)
    背景

    Synonyms: BILIQTL1,Bilirubin specific UDPGT isozyme 1 ,bilirubin UDP glucuronosyltransferase 1 1 ,bilirubin UDP glucuronosyltransferase isozyme 1 ,Bilirubin-specific UDPGT isozyme 1,EC 2.4.1.17,GNT1,HUG BR1,HUG-BR1,HUGBR1,PHENOL/BILIRUBIN UDP GLUCURONOSYLTRANSFERASE,UD11,UDP glucuronosyltransferase 1 1 [Precursor],UDP glucuronosyltransferase 1 family polypeptide A1 ,UDP glucuronosyltransferase 1A1,UDP GLYCOSYLTRANSFERASE 1,UDP-glucuronosyltransferase 1-1,UDP-glucuronosyltransferase 1-A,UDP-glucuronosyltransferase 1A1,UDPGT ,UDPGT 1-1,UGT 1A,UGT-1A,UGT1 ,UGT1 01,UGT1*1,UGT1-01,UGT1.1,UGT1A,Ugt1a1,URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE, BILIRUBIN/PHENOL,URIDINE DIPHOSPHATE GLYCOSYLTRANSFERASE 1,URIDINE DIPHOSPHATE GLYCOSYLTRANSFERASE 1 FAMILY, POLYPEPTIDE A1

    Background: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids. Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome.

    分子量

    Observed_MW: 75kDa

    Calculated_MW: 49kDa/59kDa

    基因ID
    54658
    UniProt
    P22309
    途径
    Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
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