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RENT2/UPF2 抗体

UPF2 适用: 人, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6567949
发货至: 中国
  • 抗原 See all RENT2/UPF2 (UPF2) 抗体
    RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))
    适用
    • 25
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 24
    • 1
    克隆类型
    • 25
    多克隆
    标记
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    This RENT2/UPF2 antibody is un-conjugated
    应用范围
    • 22
    • 14
    • 13
    • 5
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human UPF2 (NP_542166.1).
    亚型
    IgG
    Top Product
    Discover our top product UPF2 Primary Antibody
  • 应用备注
    IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))
    别名
    UPF2 (UPF2 产品)
    别名
    HUPF2 antibody, RENT2 antibody, smg-3 antibody, UPF2, regulator of nonsense mediated mRNA decay antibody, UPF2 regulator of nonsense transcripts homolog (yeast) antibody, UPF2 antibody, Upf2 antibody, upf2 antibody
    背景
    This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene, both variants encode the same protein.
    分子量

    Observed_MW: 180kDa

    Calculated_MW: 66kDa/147kDa

    基因ID
    26019
    UniProt
    Q9HAU5
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