FAM3B 抗体
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- 抗原 See all FAM3B 抗体
- FAM3B (Family with Sequence Similarity 3, Member B (FAM3B))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FAM3B antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human FAM3B (NP_478066.3).
- 亚型
- IgG
- Top Product
- Discover our top product FAM3B Primary Antibody
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- 应用备注
- IHC 1:100-1:200 IF 1:100-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- FAM3B (Family with Sequence Similarity 3, Member B (FAM3B))
- 别名
- FAM3B (FAM3B 产品)
- 别名
- 2-21 antibody, C21orf11 antibody, C21orf76 antibody, ORF9 antibody, PANDER antibody, 9030624C24Rik antibody, D16Jhu19e antibody, Pander antibody, RGD1311662 antibody, family with sequence similarity 3 member B antibody, family with sequence similarity 3, member B antibody, FAM3B antibody, Fam3b antibody
- 物质类
- Viral Protein
- 背景
- FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete vesicular and perinuclear structures. Expressed at high levels in pancreas and at lower levels in kidney, colon, testis, prostate and small intestine, FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit Insulin secretion from beta-cells, possibly playing a role in overall pancreatic activity. Human FAM3B shares 78 % sequence identity with its mouse counterpart, suggesting a conserved role between species. Three isoforms of FAM3B, designated A, B and C, exist due to alternative splicing events. The gene encoding FAM3B maps to human chromosome 21, which houses approximately 300 genes and comprises nearly 1.5 % of the human genome.
- 分子量
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Calculated_MW: 20kDa/25kDa/30kDa
- 基因ID
- 54097
- UniProt
- P58499
- 途径
- Hormone Transport
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