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CDK6 抗体

CDK6 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6566654
发货至: 中国
  • 抗原 See all CDK6 抗体
    CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
    适用
    • 128
    • 49
    • 26
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 111
    • 17
    克隆类型
    • 100
    • 28
    多克隆
    标记
    • 69
    • 7
    • 5
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    • 4
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    • 4
    • 4
    • 2
    • 2
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    This CDK6 antibody is un-conjugated
    应用范围
    • 77
    • 38
    • 30
    • 27
    • 27
    • 24
    • 23
    • 13
    • 8
    • 5
    • 2
    • 2
    • 2
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    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide of human CDK6
    亚型
    IgG
    Top Product
    Discover our top product CDK6 Primary Antibody
  • 应用备注
    WB 1:500-1:2000 IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
    别名
    CDK6 (CDK6 产品)
    别名
    CDK6 antibody, PLSTIRE antibody, 5830411I20 antibody, AI504062 antibody, Crk2 antibody, cyclin dependent kinase 6 antibody, cyclin-dependent kinase 6 antibody, CDK6 antibody, Cdk6 antibody
    背景
    The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified.
    分子量

    Observed_MW: 37kDa

    Calculated_MW: 36kDa

    基因ID
    1021
    UniProt
    Q00534
    途径
    Cell Division Cycle, Mitotic G1-G1/S Phases
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