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NOTCH2 抗体

NOTCH2 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6566613
发货至: 中国
  • 抗原 See all NOTCH2 抗体
    NOTCH2 (Notch 2 (NOTCH2))
    适用
    • 62
    • 55
    • 31
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 73
    • 5
    • 3
    • 1
    • 1
    克隆类型
    • 70
    • 10
    • 2
    多克隆
    标记
    • 44
    • 4
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    • 3
    • 2
    • 2
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
    This NOTCH2 antibody is un-conjugated
    应用范围
    • 48
    • 32
    • 26
    • 26
    • 17
    • 16
    • 14
    • 12
    • 7
    • 6
    • 4
    • 2
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    • 1
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    Immunohistochemistry (IHC), Immunofluorescence (IF)
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human NOTCH2 (NP_077719.2).
    亚型
    IgG
    Top Product
    Discover our top product NOTCH2 Primary Antibody
  • 应用备注
    IHC 1:100-1:200 IF 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    NOTCH2 (Notch 2 (NOTCH2))
    别名
    NOTCH2 (NOTCH2 产品)
    别名
    AGS2 antibody, HJCYS antibody, hN2 antibody, AI853703 antibody, N2 antibody, notch6 antibody, sb:cb884 antibody, neurogenic locus notch homolog protein 2 antibody, notch 2 antibody, notch 3 antibody, LOC581186 antibody, NOTCH2 antibody, notch3 antibody, Notch2 antibody, notch2 antibody
    背景
    This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. Two transcript variants encoding different isoforms have been found for this gene.
    分子量

    Observed_MW: 120kDa

    Calculated_MW: 265kDa

    基因ID
    4853
    UniProt
    Q04721
    途径
    Notch Signaling, Stem Cell Maintenance
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