兔 anti-小鼠 IgA Antibody (Cy5.5)
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- 抗原 See all IgA products
- IgA
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- Cy5.5
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 小鼠
- 纯化方法
- affinity Purified by Protein A.
- 免疫原
- Mouse IgA protein purified from serum
- 亚型
- IgG
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Goat anti-Mouse IgA (Heavy Chain) antibody
ELISA, IHC, WB, FACS Polyclonal IgG unconjugated
Goat anti-Mouse IgA (Heavy Chain) antibody (HRP)ELISA, IHC, WB Polyclonal IgG HRP
Goat anti-Mouse IgA (Heavy Chain) antibody (Alkaline Phosphatase (AP))ELISA, IHC, WB Polyclonal IgG Alkaline Phosphatase (AP)
Goat anti-Mouse IgA (Heavy Chain) antibody (Biotin)ELISA, IHC, WB, FACS Polyclonal IgG Biotin
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- 应用备注
- IF(IHC-P) 1:500-2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 注意事项
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Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed. - 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- IgA
- Abstract
- IgA 产品
- 物质类
- Antibody
- 背景
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Optional[synonyms]: Mouse IgA (immunoglobulin A) is a glycosylated protein of 160 kDa and is produced as a monomer or as a J chain-linked dimer. Monomeric IgA constitutes 5-15 % of the serum immunoglobulins whereas dimeric IgA is localized to mucosa surfaces such as saliva, gastrointestinal secretion, bronchial fluids, and milk. Mucosal IgA plays a major role in host defense by neutralizing infectious agents at mucosal surfaces. The production is usually local and antigen-specific IgA-producing B cells can be found in regions under the lamina propria where they mature into dimeric IgA-producing plasma cells. IgA deficiency is the most common immunodeficiency that may affect both serum and mucosal-produced IgA. OR: The secretory component is a component of immunoglobulin A (IgA) which consists of a portion of the polymeric immunoglobulin receptor. Polymeric IgA binds to the polymeric immunoglobulin receptor on the basolateral surface of epithelial cells and is taken up into the cell via transcytosis. The receptor-IgA complex passes through the cellular compartments before being secreted on the luminal surface of the epithelial cells, still attached to the receptor. Proteolysis of the receptor occurs and the dimeric IgA molecule, along with the secretory component, are free to diffuse throughout the lumen.
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