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- 抗原 See all CPSF4 抗体
- CPSF4 (Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4))
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抗原表位
- AA 96-123
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CPSF4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 预测反应
- B, Rat, X
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This CPSF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-123 amino acids from the Central region of human CPSF4.
- 克隆位点
- RB23266
- 亚型
- Ig Fraction
- Top Product
- Discover our top product CPSF4 Primary Antibody
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anti-Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) (AA 1-244) antibody
CPSF4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) (AA 81-180) antibodyCPSF4 适用: 人, 小鼠 WB, ELISA, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) (C-Term) antibodyCPSF4 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) antibodyCPSF4 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) (AA 1-243) antibodyCPSF4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) (C-Term) antibodyCPSF4 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) (AA 31-216) antibodyCPSF4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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- 抗原
- CPSF4 (Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4))
- 别名
- CPSF4 (CPSF4 产品)
- 背景
- Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain. The NS1 effector domain functionally interacts with the cellular 30 kDa subunit of cleavage and polyadenylation specific factor 4, an essential component of the 3' end processing machinery of cellular pre-mRNAs. In influenza virus-infected cells, the NS1 protein is physically associated with cleavage and polyadenylation specific factor 4, 30kD subunit. Binding of the NS1 protein to the 30 kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end cleavage and polyadenylation of host pre-mRNAs. Thus the NS1 protein selectively inhibits the nuclear export of cellular, and not viral, mRNAs.
- 分子量
- 30255
- 基因ID
- 10898
- NCBI登录号
- NP_001075028, NP_006684
- UniProt
- O95639
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