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DFFA 抗体 (C-Term)

DFFA 适用: 人 WB 宿主: 兔 Polyclonal RB23680 unconjugated
产品编号 ABIN653234
发货至: 中国
  • 抗原 See all DFFA 抗体
    DFFA (DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA))
    抗原表位
    • 15
    • 13
    • 9
    • 7
    • 6
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 304-331, C-Term
    适用
    • 73
    • 33
    • 20
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 75
    • 9
    • 1
    克隆类型
    • 77
    • 8
    多克隆
    标记
    • 61
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DFFA antibody is un-conjugated
    应用范围
    • 82
    • 30
    • 15
    • 14
    • 13
    • 13
    • 12
    • 10
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This DFFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-331 amino acids from the C-terminal region of human DFFA.
    克隆位点
    RB23680
    亚型
    Ig Fraction
    Top Product
    Discover our top product DFFA Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    DFFA (DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA))
    别名
    DFFA (DFFA 产品)
    别名
    DFF-45 antibody, DFF1 antibody, ICAD antibody, A330085O09Rik antibody, DFF35 antibody, Dff45 antibody, ICAD-L antibody, ICAD-S antibody, DFFA antibody, zgc:92229 antibody, DNA fragmentation factor subunit alpha antibody, DNA fragmentation factor, alpha subunit antibody, DNA fragmentation factor, 45kDa, alpha polypeptide antibody, DNA fragmentation factor, alpha polypeptide antibody, DFFA antibody, Dffa antibody, dffa antibody
    背景
    DFFA is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis.
    分子量
    36522
    基因ID
    1676
    NCBI登录号
    NP_004392, NP_998731
    UniProt
    O00273
    途径
    Apoptosis, Caspase Cascade in Apoptosis
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