我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

IL-1 beta 抗体 (AA 148-174)

Name: IL-1 beta 抗体 (AA 148-174)
SKU: ABIN652470
Availability: OutOfStock

IL1B 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21917 unconjugated

All lanes : Anti-IL1B Antibody (Center) at 1:2000 dilution Lane 1: human spleen lysate Lane 2: mouse brain lysate Lysates/proteins at 20 μg per lane.

Formalin-fixed and paraffin-embedded human lung carcinoma with IL1B Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

IHC (p)

Western blot analysis of IL1B Antibody (Center) (ABIN652470 and ABIN2842321) in NCI- cell line lysates (35 μg/lane).

Overlay histogram showing MCF-7 cells stained with (ABIN652470 and ABIN2842321) (green line).

FACS

4 images

(4 references)

产品编号 ABIN652470

发货至: 中国

Datasheet as PDF

抗原 See all IL-1 beta (IL1B) 抗体

IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
抗原表位
17

15

15

15

9

8

7

7

6

6

5

5

5

4

4

4

4

3

3

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 148-174
适用
121

86

43

28

24

14

8

8

8

7

5

3

3

1

1

1
人, 小鼠
宿主
173

64

6

6

4

2

1
兔
Compatible Secondaries
克隆类型
180

74

1
多克隆
标记
134

40

23

10

7

5

4

4

3

3

3

3

3

3

2

2

2

2

2

2
This IL-1 beta antibody is un-conjugated
应用范围
182

107

90

46

42

39

28

17

16

15

14

14

11

10

8

8

6

4

3

3

3

3

2

1

1

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

预测反应

Pr, Rb

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This IL1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-174 amino acids of human IL1B.

克隆位点

RB21917

亚型

IgG

Top Product

Discover our top product IL1B Primary Antibody
anti-Interleukin 1, beta (IL1B) (AA 101-200) antibody
IL1B 适用: 人, 小鼠, 大鼠, Cow, 兔, Pig WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro), DB 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 1, beta (IL1B) (AA 161-269) antibody
IL1B 适用: 人, 小鼠, 大鼠, Cow, 兔 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 1, beta (IL1B) antibody
IL1B 适用: 人 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 3A6 unconjugated

anti-Interleukin 1, beta (IL1B) (AA 170-269) antibody
IL1B 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 2A8 unconjugated

anti-Interleukin 1, beta (IL1B) (AA 117-269) antibody
IL1B 适用: 人 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 5C3B7 unconjugated

anti-Interleukin 1, beta (IL1B) (AA 117-269) antibody
IL1B 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 6F12D5 unconjugated

anti-Interleukin 1, beta (IL1B) (AA 1-266) antibody
IL1B 适用: 绵羊 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 1, beta (IL1B) antibody
IL1B 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 1, beta (IL1B) (AA 1-269) antibody
IL1B 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 1, beta (IL1B) antibody
IL1B 适用: 小鼠, 大鼠 WB, ELISA, IHC, IP, FACS, Neut, RIA 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:2000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:25

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Abdul-Muneer, Alikunju, Mishra, Schuetz, Szlachetka, Burnham, Haorah: "Activation of NLRP3 inflammasome by cholesterol crystals in alcohol consumption induces atherosclerotic lesions." in: Brain, behavior, and immunity, Vol. 62, pp. 291-305, (2018) (PubMed).

Liu, Wen, Chen, Wang, Huang, Tu: "Effects of Berberine on NLRP3 and IL-1β Expressions in Monocytic THP-1 Cells with Monosodium Urate Crystals-Induced Inflammation." in: BioMed research international, Vol. 2016, pp. 2503703, (2016) (PubMed).

Zhang, Liu, Huang, Su, Zhang, Wang, Li: "NF-?B activation and cell death after intracerebral hemorrhage in patients." in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, Vol. 35, Issue 7, pp. 1097-102, (2014) (PubMed).

Liu, Tu, Chen, Wang, Hu, Dong: "Effects of Modified Simiao Decoction on IL-1 β and TNF α Secretion in Monocytic THP-1 Cells with Monosodium Urate Crystals-Induced Inflammation." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 406816, (2014) (PubMed).
抗原

IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

别名

IL1B (IL1B 产品)

别名

IL-1 antibody, IL1-BETA antibody, IL1F2 antibody, IL-1BETA antibody, IL1beta antibody, il1-b antibody, zgc:111873 antibody, IL-1B antibody, IL-1beta antibody, Il-1b antibody, IL1B antibody, IL-1 beta antibody, IL-1b antibody, interleukin 1 beta antibody, interleukin 1, beta antibody, IL1B antibody, il1b antibody, Il1b antibody

背景

IL1B is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (,CNS), is found to contribute to inflammatory pain hypersensitivity.

分子量

30748

基因ID

3553

NCBI登录号

NP_000567

UniProt

P01584

途径

NF-kappaB Signaling, Interferon-gamma Pathway, TLR signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome